NovMetaPharma Co., Ltd.
KONEX-listed biotech developing NovDB2, NovDKD, and NovFSHD drug pipelines for metabolic disease and fibrosis.
As of 2026-10-10, NovMetaPharma Co., Ltd. has 21 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Change
Market cap
Business overview
Source: DART corporate disclosureFounded in 2010 and listed on KONEX in 2015, NovMetaPharma develops drugs for metabolic, inflammatory, and fibrotic diseases. Its pipeline centers on diabetes drug NovDB2, kidney drug NovDKD, and FSHD drug NovFSHD, plus health food sales and C01 skin booster marketing. It targets Phase 2 before out-licensing, with Phase 2b done for NovDB2/NovOB and IRB approval for NovDKD's Phase 2 trial.
Products & technology
- 신약 관련 원료
- 건강기능식품
- C01 기반 스킨부스터
Clinical trials
data.go.kr1 MFDS clinical trial authorisations · 2023 (Phase 2 1)
- Phase 2Cyclo-Z2023-03-14
14 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 2 · Completed · 2018-06 · NCT03560271
Phase 2 · Completed · 2016-06 · NCT02784275
R&D and key agreements
Source: DART corporate disclosureNovDB2 · 2형 당뇨병 · 미국 임상 2b상 완료 · Novel-mechanism insulin resistance drug; follow-up trial integrated into the NovDKD Phase 2 program
NovDKD · 당뇨병콩팥병 · 국내 임상 2상(2024년 2분기 IRB 승인 완료) · Novel-substance kidney disease drug; safety verified through FDA Phase 2b in type 2 diabetes patients
NovFSHD / NovFSHD2 · FSHD(안면견갑상완근위축증) · 2026년 중 임상 2상 진입 예정(일반인 대상 1상 완료) · Efficacy verified in animal models by a major North American FSHD institution
NovOB-M · GLP1 비만치료제 관련 근감소증 · 1상 완료(일반인 대상) · Studied as a co-administered therapy with GLP-1 obesity drugs to address muscle loss/function decline
NovFS-IP · 특발성 폐섬유증 · 1상 완료(일반인 대상) · FDA orphan drug designation granted; safety verified through FDA Phase 2b in type 2 diabetes patients
NovSR · 근감소증(노화 관련) · 1상 진입 예정(IND 안전성 자료 확보)
NovDMD · 듀센근이영양증 · 1상 예정(IND 안전성 자료 완료) · Related research published in Advanced Science (2024)
NovAP · 급성췌장염 · 전임상 · Novel-mechanism drug; seeking a partner for out-licensing/co-development
NovLC · 간암 · 전임상 · Shown potential to overcome sorafenib resistance; seeking an out-licensing partner
Publications
PubMed · affiliation-matched- Intra-Articular Cyclo(His-Pro) Attenuates Monosodium Iodoacetate-Induced Osteoarthritis by Suppressing COX-2/PGE2 Signaling and Cartilage Catabolism in Rats.
International journal of molecular sciences · 2026-05 · Huh G, Lee D, Jeon J 외 2
- Combined Histidine and Proline Supplementation (HISPRO) Enhances Oxidative and Mitochondrial Function in Skeletal Muscle Through SIRT1-Associated Signaling.
Cells · 2026-05 · Lee D, Jeon J, Huh G 외 7
- Uncovering a Glaucoma-Linked Lysophosphatidic Acid-MAPK/AP-1 Fibrosis Axis in Human Trabecular Meshwork Cells and Its Modulation by Diospyros kaki Leaf Extract.
International journal of molecular sciences · 2026-02 · Jeon Y, Kwon H, Ahn HR 외 8
- CycloZ Suppresses TLR4-Driven Inflammation to Reduce Asthma-Like Responses in HDM-Exposed Mouse Models.
Cells · 2024-12 · Lee D, Jeon J, Baek S 외 4
- Protective effect of Cyclo(His-Pro) on peritoneal fibrosis through regulation of HDAC3 expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024-07 · Kim JE, Han D, Kim KH 외 14
- Cyclo His-Pro Attenuates Muscle Degeneration in Murine Myopathy Models.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024-07 · De Masi A, Zanou N, Strotjohann K 외 7
- Inhibition of chloride intracellular channel protein 1 (CLIC1) ameliorates liver fibrosis phenotype by activating the Ca2+-dependent Nrf2 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023-12 · Ko M, Jung HY, Lee D 외 6
- CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice.
Diabetes & metabolism journal · 2023-09 · Jeon J, Lee D, Kim B 외 13
- Cyclo(His-Pro): A further step in the management of steatohepatitis.
JHEP reports : innovation in hepatology · 2023-09 · De Masi A, Li X, Lee D 외 9
- Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
Proceedings of the National Academy of Sciences of the United States of America · 2023-05 · Chanda D, Thoudam T, Sinam IS 외 20
Show 11 more publications
- Vaccinia-related kinase 2 variants differentially affect breast cancer growth by regulating kinase activity.
Oncology research · 2023-01 · Gwak SH, Lee J, Oh E 외 4
- Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ.
Alzheimer's research & therapy · 2022-10 · Jo KW, Lee D, Cha DG 외 6
- Betulinic acid inhibits high-fat diet-induced obesity and improves energy balance by activating AMPK.
Nutrition, metabolism, and cardiovascular diseases : NMCD · 2019-04 · Kim KD, Jung HY, Ryu HG 외 10
- Vaccinia-related kinase 2 modulates role of dysbindin by regulating protein stability.
Journal of neurochemistry · 2018-12 · Jeong YH, Choi JH, Lee D 외 2
- Amodiaquine improves insulin resistance and lipid metabolism in diabetic model mice.
Diabetes, obesity & metabolism · 2018-07 · Jung HY, Kim B, Ryu HG 외 13
- Sepsis-Like Systemic Inflammation Induced by Nano-Sized Extracellular Vesicles From Feces.
Frontiers in microbiology · 2018-01 · Park KS, Lee J, Lee C 외 9
- Specificity and putative mode of action of a mosquito larvicidal toxin from the bacterium Xenorhabdus innexi.
Journal of invertebrate pathology · 2017-10 · Kim IH, Ensign J, Kim DY 외 6
- A guanidine-appended scyllo-inositol derivative AAD-66 enhances brain delivery and ameliorates Alzheimer's phenotypes.
Scientific reports · 2017-10 · Lee D, Lee WS, Lim S 외 7
- Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α.
Scientific reports · 2017-07 · Jung HY, Lee D, Ryu HG 외 17
- Hyaluronate-Death Receptor 5 Antibody Conjugates for Targeted Treatment of Liver Metastasis.
Biomacromolecules · 2016-09 · Lee H, Hong BJ, Lee JH 외 5
- A Fomitopsis pinicola Jeseng Formulation Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity.
Evidence-based complementary and alternative medicine : eCAM · 2016-01 · Jung HY, Ji Y, Kim NR 외 3
Patents
KIPRIS · applicant-matchedPublished · 2026-08 · Application 1020260156723
PCT · Published · 2026-01 · Application PCT/KR2026/000763
Published · 2026-01 · Application 1020260006463
US · Published · 2025-12 · Application 19435309
PCT · Published · 2025-04 · Application PCT/KR2025/005931
Published · 2025-04 · Application 1020250057635
PCT · Published · 2024-12 · Application PCT/KR2024/020629
US · Published · 2024-11 · Application 18954719
PCT · Published · 2024-11 · Application PCT/KR2024/017882
PCT · Published · 2024-11 · Application PCT/KR2024/017546
Show 141 more patents
PCT · Published · 2024-10 · Application PCT/KR2024/015884
Published · 2024-10 · Application 1020240142643
EP · Published · 2024-10 · Application 24932088.8
PCT · Published · 2024-10 · Application PCT/KR2024/014934
Published · 2024-04 · Application 1020240056071
Published · 2024-03 · Application 1020240041829
Rejected · 2024-02 · Application 1020240029212
US · Published · 2024-01 · Application 18427249
PCT · Published · 2024-01 · Application PCT/IB2024/050860
Registered · 2023-12 · Application 1020230185147
Published · 2023-12 · Application 1020230183097
US · Published · 2023-12 · Application 18533699
EP · Published · 2023-12 · Application 23900171.2
PCT · Published · 2023-12 · Application PCT/IB2023/062417
Published · 2023-12 · Application 1020257022893
Rejected · 2023-11 · Application 1020230153151
US · Published · 2023-10 · Application 18385686
US · Registered · 2023-10 · Application 18377656
US · Published · 2023-09 · Application 18476630
Published · 2023-09 · Application 1020257014084
EP · Published · 2023-09 · Application 23871195.6
PCT · Published · 2023-09 · Application PCT/IB2023/059697
Rejected · 2023-09 · Application 1020230129417
US · Published · 2023-08 · Application 19107159
EP · Published · 2023-08 · Application 23860880.6
PCT · Published · 2023-08 · Application PCT/KR2023/012909
EP · Published · 2023-08 · Application 23850462.5
PCT · Published · 2023-08 · Application PCT/KR2023/011420
US · Published · 2023-07 · Application 18996559
EP · Published · 2023-07 · Application 23843355.1
PCT · Published · 2023-07 · Application PCT/KR2023/010378
US · Published · 2023-06 · Application 18204520
EP · Published · 2023-06 · Application 23815413.2
PCT · Published · 2023-06 · Application PCT/IB2023/055661
Published · 2023-06 · Application 1020257000132
US · Published · 2022-11 · Application 18712003
EP · Published · 2022-11 · Application 22896171.0
PCT · Published · 2022-11 · Application PCT/KR2022/018469
Rejected · 2022-11 · Application 1020220155606
PCT · Published · 2022-11 · Application PCT/KR2022/018334
Rejected · 2022-08 · Application 1020220110114
Published · 2022-08 · Application 1020220096513
Registered · 2022-07 · Application 1020220089073
US · Published · 2022-07 · Application 18577804
PCT · Published · 2022-07 · Application PCT/KR2022/010372
US · Registered · 2022-07 · Application 17856729
US · Registered · 2022-06 · Application 17852774
Published · 2021-12 · Application 1020237024610
EP · Published · 2021-12 · Application 21905957.3
PCT · Published · 2021-12 · Application PCT/IB2021/061882
Registered · 2021-11 · Application 1020210161115
US · Published · 2021-08 · Application 17406626
EP · Published · 2021-08 · Application 21857893.8
PCT · Published · 2021-08 · Application PCT/KR2021/011037
PCT · Published · 2021-08 · Application PCT/IB2021/057653
Rejected · 2021-08 · Application 1020237009443
CN · Published · 2021-08 · Application 202180057678.1
Registered · 2021-08 · Application 1020237007726
EP · Published · 2021-08 · Application 21853493.1
Registered · 2021-07 · Application 1020210093258
CN · Published · 2021-06 · Application 202180044757.9
EP · Registered · 2021-06 · Application 21828157.4
Registered · 2021-06 · Application 1020237002940
US · Registered · 2021-06 · Application 17350170
PCT · Published · 2021-06 · Application PCT/IB2021/055375
Rejected · 2021-06 · Application 1020237002015
Registered · 2021-05 · Application 1020210069267
CN · Published · 2021-03 · Application 202180022746.0
US · Registered · 2021-03 · Application 17912942
EP · Published · 2021-03 · Application 21770955.9
PCT · Published · 2021-03 · Application PCT/KR2021/003424
Registered · 2021-03 · Application 1020210036268
US · Registered · 2021-02 · Application 17172879
US · Published · 2020-11 · Application 17779826
EP · Published · 2020-11 · Application 20894718.4
Registered · 2020-11 · Application 1020200161456
Registered · 2020-08 · Application 1020200104159
PCT · Published · 2020-07 · Application PCT/KR2020/010080
Registered · 2020-07 · Application 1020200095466
PCT · Published · 2020-07 · Application PCT/KR2020/009914
US · Registered · 2020-06 · Application 16908195
US · Registered · 2020-06 · Application 16901676
CN · Published · 2020-05 · Application 202080036859.1
US · Published · 2020-05 · Application 17612038
EP · Registered · 2020-05 · Application 20810761.5
PCT · Published · 2020-05 · Application PCT/KR2020/006491
PCT · Published · 2020-04 · Application PCT/KR2020/005726
EP · Registered · 2020-04 · Application 20806509.4
CN · Published · 2020-03 · Application 202080025936.3
CN · Published · 2020-03 · Application 202080026734.0
US · Published · 2020-03 · Application 17599211
EP · Published · 2020-03 · Application 20777378.9
EP · Registered · 2020-03 · Application 20776685.8
PCT · Published · 2020-03 · Application PCT/KR2020/004343
PCT · Published · 2020-03 · Application PCT/KR2020/004354
Registered · 2020-03 · Application 1020200037859
Registered · 2020-03 · Application 1020200037858
US · Published · 2019-11 · Application 17292238
Registered · 2019-08 · Application 1020190098520
Registered · 2019-07 · Application 1020190092757
CN · Published · 2019-06 · Application 201980046575.8
US · Registered · 2019-06 · Application 16448083
EP · Published · 2019-06 · Application 23193616.2
EP · Registered · 2019-06 · Application 19834745.2
PCT · Published · 2019-06 · Application PCT/US2019/038391
Withdrawn · 2019-06 · Application 1020217004022
Published · 2019-06 · Application 1020257036281
Registered · 2019-05 · Application 1020190058369
US · Published · 2019-04 · Application 16398421
US · Published · 2018-12 · Application 16956109
PCT · Published · 2018-12 · Application PCT/KR2018/015720
CN · Published · 2018-11 · Application 201880074979.3
US · Registered · 2018-11 · Application 16764913
Registered · 2018-11 · Application 1020180143641
EP · Registered · 2018-11 · Application 18879826.8
Rejected · 2018-11 · Application 1020180136015
CN · Published · 2018-10 · Application 201880068309.0
US · Registered · 2018-10 · Application 16757575
EP · Registered · 2018-10 · Application 18867498.0
Registered · 2018-10 · Application 1020180125564
CN · Published · 2018-09 · Application 201880069086.X
EP · Published · 2018-09 · Application 18869973.0
PCT · Published · 2018-09 · Application PCT/KR2018/011130
Registered · 2018-01 · Application 1020180012047
Rejected · 2017-12 · Application 1020170176322
Registered · 2017-10 · Application 1020170141167
CN · Published · 2017-08 · Application 201780049430.4
US · Registered · 2017-08 · Application 16324784
EP · Published · 2017-08 · Application 17839896.2
Registered · 2017-08 · Application 1020170103181
CN · Published · 2017-07 · Application 202110619829.X
CN · Published · 2017-07 · Application 201780042925.4
EP · Registered · 2017-07 · Application 20206943.1
EP · Registered · 2017-07 · Application 17827971.7
Registered · 2017-07 · Application 1020170088341
- NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT
EP · Registered · 2016-09 · Application 16907430.9
CN · Published · 2016-02 · Application 201680010312.8
US · Registered · 2016-02 · Application 15551310
EP · Published · 2016-02 · Application 16752682.1
Registered · 2016-02 · Application 1020160017960
Registered · 2008-02 · Application 1020097020578
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Organoid-based biotech founded 2018, KOSDAQ-listed 2025, developing the ATORM-C regenerative therapeutic and ODISEI evaluation solution.
EDGC, a Korea-US joint venture of Eone Medical Foundation and Diagnomics, offers the NIPT service NICE and liquid biopsy OncoCatch.
A diversified SK group company operating eco-friendly chemical materials alongside pharmaceutical products like Joins and vaccines through subsidiary SK Bioscience.
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KOSDAQ-listed antibody biotech developing the next-generation immuno-oncology candidate Multi-AbKine on its fully human antibody library Ymax®-ABL.
A holding company overseeing 54 affiliates including its main biopharmaceutical subsidiary GC, with no direct product manufacturing of its own.
Founded in 2015 and listed on KOSPI in 2021, Prestige BioPharma develops antibody biosimilars and novel antibody drugs including Tuznue.
KOSDAQ-listed biotech company developing molecular diagnostics with proprietary C-Tag technology and the NeoPlex product line.
SillaJen, Inc., founded in 2006 and listed on KOSDAQ in 2016, develops the oncolytic virus immunotherapy Pexa-Vec.
A vaccine specialist developing in-house products such as SKYCellflu and SKYZoster while also serving as CDMO for AstraZeneca and Novavax.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
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- DART corporate disclosure filings — annual
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- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
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- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
- AI visibility
- Measured 2026-10-01
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