ORGANOIDSCIENCES LTD.
Organoid-based biotech founded 2018, KOSDAQ-listed 2025, developing the ATORM-C regenerative therapeutic and ODISEI evaluation solution.
As of 2026-10-10, ORGANOIDSCIENCES LTD. has 34 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Business overview
Source: DART corporate disclosureORGANOIDSCIENCES LTD. was founded in October 2018 and listed on the KOSDAQ market in May 2025 as an organoid-based biotech company. Its core business spans the intestinal organoid therapeutic ATORM-C built on the ATORM regenerative-therapeutics platform, the new-material evaluation solution ODISEI, and the research reagent brand organoEZ. The tumor organoid evaluation solution ODISEI-ONC was commercialized in 2020, ODISEI uses more than 20 types of organ-specific organoids, and the company has also expanded into immuno-oncology precision medicine and cell/tissue-engineering CDMO services.
Products & technology
- ATORM-CSingle local-administration therapeutic derived from adult stem cell-based intestinal organoids for refractory intestinal ulcers (IBD, Behcet's enteritis, radiation proctitis, stercoral ulcer)
- ODISEIOrganoid-based new-material evaluation solution predicting human-body effects of new materials for drugs, food, and cosmetics, using more than 20 types of organ-specific organoids (tumor, virus, intestine, skin, etc.)
- organoEZCustomized organoid research reagent product line leveraging the company's culture know-how
Clinical trials
data.go.kr1 MFDS clinical trial authorisations · 2026 (Phase 1 1)
- Phase 1ATORM-C2026-03-13
2 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 1 · Recruiting · 2026-09 · NCT07822087
R&D and key agreements
Source: DART corporate disclosureATORM-C · 난치성 장궤양(염증성 장질환(IBD), 베체트 장염, 방사선 직장염, 숙변성 궤양 등) · 첨단재생의료 임상연구(2022년 보건복지부 승인, 진행중) · In December 2025, filed an IND application with the MFDS for a Phase 1 clinical trial in patients with Crohn's disease accompanied by colonic ulcers
Key disclosures
KRX KIND via OpenDARTPublications
PubMed · affiliation-matched- New approach methodologies for next-generation risk assessment of nanomaterials and nano-enabled products.
Nano convergence · 2026-07 · Lee E, Chary A, Gerelkhuu Z 외 37
- Neural dynamics of temporal interference stimulation monitoring by soft liquid metal interfaces across neural systems.
Nature communications · 2026-07 · Kim E, Park W, Hong YM 외 9
- Sphingosine-1-phosphate receptor 1 signaling stimulates human pluripotent stem cell-derived cardiomyocyte differentiation and maturation.
Experimental & molecular medicine · 2026-07 · Yu WD, Lee SG, Jung KB 외 12
- Inflammation Disrupts Ganglioside Expression during Early Embryonic Development in Institute of Cancer Research (ICR) Mice: Protective Effects of Melatonin.
Development & reproduction · 2026-06 · Yun HG, Song EB, Kwak DH 외 3
- Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research.
Journal of dermatological science · 2026-06 · Kyung S, Lim SJ, Lee KE 외 8
- Drug-induced gastrointestinal toxicity and barrier integrity: cytoskeleton-mediated impairment in a clinically relevant human intestinal epithelium model.
Experimental & molecular medicine · 2026-03 · Yu WD, Lee S, Cho HS 외 9
- Biobanking of gynecologic cancer biospecimens: Development, quality control, and translational applications.
PloS one · 2026-01 · Kim JY, Lee YK, Shin HY 외 8
- Multiplexed imaging-driven single-cell analysis of abdominal aortic aneurysm according to C-reactive protein deposition.
Translational research : the journal of laboratory and clinical medicine · 2025-08 · Kim EN, Seok HY, Koh J 외 12
- Current status and future prospects of toxicity assessment using organoids.
Toxicological research · 2025-07 · Nguyen XH, Yoo J
- SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases.
Cell reports · 2025-05 · Ku D, Yang Y, Park Y 외 15
Show 24 more publications
- Function of Immune Checkpoints in IgG4-Related Disease with Lacrimal Gland Involvement: Clinical Features, Serum IgG4 Level, Immunohistochemical Landscape, and Treatment Responses.
International journal of molecular sciences · 2025-03 · Bae DH, Kim YR, Yang W 외 3
- Exploring the characteristics of immortalized human ovarian surface epithelial cell lines.
Heliyon · 2025-02 · Shin HY, Yang W, Kim JY 외 6
- Ex vivo enhancement of CD8+ T cell activity using functionalized hydrogel encapsulating tonsil-derived lymphatic endothelial cells.
Theranostics · 2025-01 · Hong H, Park CH, Lee JS 외 12
- Xenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy.
Nature communications · 2024-12 · Park S, Kwon O, Lee H 외 20
- Unraveling the Molecular Landscape of SCN1A Gene Knockout in Cerebral Organoids: A Multiomics Approach Utilizing Proteomics, Lipidomics, and Transcriptomics.
ACS omega · 2024-09 · Koh B, Kim YE, Park SB 외 10
- Salivary gland organoid transplantation as a therapeutic option for radiation-induced xerostomia.
Stem cell research & therapy · 2024-08 · Jeon SG, Lee J, Lee SJ 외 11
- SLIRP promotes autoimmune diseases by amplifying antiviral signaling via positive feedback regulation.
bioRxiv : the preprint server for biology · 2024-06 · Ku D, Yang Y, Park Y 외 15
- Fabrication of atelocollagen-coated bioabsorbable suture and the evaluation of its regenerative efficacy in Achilles tendon healing using a rat experimental model.
International journal of biological macromolecules · 2024-06 · Yeo YH, Jo SK, Kim MH 외 9
- Standardization and quality assessment for human intestinal organoids.
Frontiers in cell and developmental biology · 2024-01 · Lee H, Yang S, Lee KJ 외 12
- Novel Organoid Culture System for Improved Safety Assessment of Nanomaterials.
Nano letters · 2024-01 · Baek A, Kwon IH, Lee DH 외 5
- Biomechanical and Biological Assessment of Polyglycelrolsebacate-Coupled Implant with Shape Memory Effect for Treating Osteoporotic Fractures.
Bioengineering (Basel, Switzerland) · 2023-12 · Park S, Lee SJ, Park KM 외 1
- Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer.
Cancer biology & therapy · 2023-12 · Kang HW, Kim JH, Lee DE 외 9
- Prostaglandin F2α analogue, bimatoprost ameliorates colistin-induced nephrotoxicity.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023-12 · Joo L, Jeong HY, Bae DH 외 9
- Current status and prospects of organoid-based regenerative medicine.
BMB reports · 2023-01 · Choi WH, Bae DH, Yoo J
- Effects of Sevoflurane Exposure on Fetal Brain Development Using Cerebral Organoids.
Journal of molecular neuroscience : MN · 2022-12 · Lee JA, Bae DH, Choi WH 외 3
- Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder.
Molecular psychiatry · 2022-11 · Kim IB, Lee T, Lee J 외 17
- Alternative splicing variant of NRP/B promotes tumorigenesis of gastric cancer.
BMB reports · 2022-07 · Kim A, Mok BR, Hahn S 외 3
- Corrigendum to "A simple and efficient cryopreservation method for mouse small intestinal and colon organoids for regenerative medicine" [Biochem. Biophys. Res. Commun. 595 (2022) 14-21].
Biochemical and biophysical research communications · 2022-04 · Lee BE, Lee BJ, Lee KJ 외 4
- Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts.
Cancers · 2022-04 · Go YH, Choi WH, Bae WJ 외 9
- Generation of human tonsil epithelial organoids as an ex vivo model for SARS-CoV-2 infection.
Biomaterials · 2022-04 · Kim HK, Kim H, Lee MK 외 13
- A simple and efficient cryopreservation method for mouse small intestinal and colon organoids for regenerative medicine.
Biochemical and biophysical research communications · 2022-03 · Lee BE, Lee BJ, Lee KJ 외 4
- Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid.
Cells · 2021-11 · Lee BE, Kim DK, Lee H 외 4
- Functional recovery by colon organoid transplantation in a mouse model of radiation proctitis.
Biomaterials · 2021-08 · Jee J, Park JH, Im JH 외 16
- Establishment of functional epithelial organoids from human lacrimal glands.
Stem cell research & therapy · 2021-04 · Jeong SY, Choi WH, Jeon SG 외 6
Patents
KIPRIS · applicant-matchedUS · Published · 2025-05 · Application 19197955
PCT · Published · 2024-12 · Application PCT/KR2024/020422
PCT · Published · 2024-12 · Application PCT/KR2024/019510
Published · 2024-12 · Application 1020240176955
Published · 2024-05 · Application 1020240068881
Registered · 2024-01 · Application 1020240006282
US · Published · 2023-11 · Application 19134020
PCT · Published · 2023-11 · Application PCT/KR2023/018875
US · Published · 2023-10 · Application 18563758
EP · Published · 2023-10 · Application 23875244.8
Show 53 more patents
PCT · Published · 2023-10 · Application PCT/KR2023/015359
EP · Published · 2023-07 · Application 23840032.9
PCT · Published · 2023-07 · Application PCT/KR2023/010229
US · Published · 2023-06 · Application 18563649
EP · Published · 2023-06 · Application 23824268.9
PCT · Published · 2023-06 · Application PCT/KR2023/008323
PCT · Published · 2023-06 · Application PCT/KR2023/008325
Rejected · 2023-05 · Application 1020230057355
PCT · Published · 2023-04 · Application PCT/KR2023/005508
Registered · 2022-11 · Application 1020220165265
US · Published · 2022-11 · Application 18013789
EP · Published · 2022-11 · Application 22935899.9
PCT · Published · 2022-11 · Application PCT/KR2022/017750
US · Published · 2022-10 · Application 18703009
PCT · Published · 2022-10 · Application PCT/KR2022/015984
Rejected · 2022-10 · Application 1020220135290
Registered · 2022-10 · Application 1020220127416
EP · Published · 2022-09 · Application 22808932.2
US · Published · 2022-09 · Application 17928829
US · Registered · 2022-09 · Application 18013770
EP · Registered · 2022-09 · Application 22798051.3
PCT · Published · 2022-09 · Application PCT/KR2022/013919
PCT · Published · 2022-09 · Application PCT/KR2022/013907
Registered · 2022-08 · Application 1020220099498
Registered · 2022-08 · Application 1020220096407
Registered · 2022-07 · Application 1020220095105
Registered · 2022-07 · Application 1020220092787
Registered · 2022-07 · Application 1020220087838
Registered · 2022-06 · Application 1020220073117
Registered · 2022-06 · Application 1020220073120
Registered · 2022-06 · Application 1020220069809
PCT · Published · 2022-04 · Application PCT/KR2022/005752
Registered · 2022-03 · Application 1020220039992
Registered · 2022-02 · Application 1020220021691
Registered · 2021-09 · Application 1020210127573
Registered · 2021-09 · Application 1020210124721
Registered · 2021-09 · Application 1020210124736
Registered · 2021-06 · Application 1020210072919
EP · Published · 2020-10 · Application 20874547.1
PCT · Published · 2020-10 · Application PCT/KR2020/013714
EP · Registered · 2019-10 · Application 19890365.0
CN · Published · 2019-10 · Application 201980090843.6
US · Registered · 2019-10 · Application 17298833
PCT · Published · 2019-10 · Application PCT/KR2019/013527
Registered · 2019-10 · Application 1020190126284
Rejected · 2018-11 · Application 1020180152804
Registered · 2018-11 · Application 1020180146773
Rejected · 2018-11 · Application 1020180141128
Registered · 2018-09 · Application 1020180114364
Registered · 2018-09 · Application 1020180114363
Registered · 2018-06 · Application 1020180074868
US · Registered · 2018-05 · Application 16618268
Registered · 2018-04 · Application 1020180039845
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How to connect (MCP)Companies in the same categoryBiotech & Drug Discovery
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Drug delivery system company behind the long-acting injectable platform IVL-DrugFluidic and the LNP delivery platform IVL-GeneFluidic.
EDGC, a Korea-US joint venture of Eone Medical Foundation and Diagnomics, offers the NIPT service NICE and liquid biopsy OncoCatch.
A diversified SK group company operating eco-friendly chemical materials alongside pharmaceutical products like Joins and vaccines through subsidiary SK Bioscience.
Genomics and drug developer behind the osteoarthritis drug Acelex and the AI-driven healthcare platform Invites Loop.
KOSDAQ-listed antibody biotech developing the next-generation immuno-oncology candidate Multi-AbKine on its fully human antibody library Ymax®-ABL.
A holding company overseeing 54 affiliates including its main biopharmaceutical subsidiary GC, with no direct product manufacturing of its own.
Founded in 2015 and listed on KOSPI in 2021, Prestige BioPharma develops antibody biosimilars and novel antibody drugs including Tuznue.
KOSDAQ-listed biotech company developing molecular diagnostics with proprietary C-Tag technology and the NeoPlex product line.
SillaJen, Inc., founded in 2006 and listed on KOSDAQ in 2016, develops the oncolytic virus immunotherapy Pexa-Vec.
A vaccine specialist developing in-house products such as SKYCellflu and SKYZoster while also serving as CDMO for AstraZeneca and Novavax.
Medipost, founded in 2000 and KOSDAQ-listed in 2005, specializes in cord blood banking and stem cell therapeutics.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
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- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
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- Measured 2026-10-01
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