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Biotech & Drug DiscoveryKOSDAQ 0868905 approvals9 trials

ISU Abxis Co., Ltd.

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KOSDAQ-listed pharma company selling Abcertin, Fabagal, and Clotinab antibody/enzyme therapies while co-developing a hemophilia drug with Catalyst Biosciences.

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Business overview

Source: DART corporate disclosure

Founded in 2001 and listed on KOSDAQ in 2009, ISU Abxis is a pharmaceutical company specializing in antibody and enzyme replacement therapies. It sells Abcertin, Fabagal, and Clotinab as its main products, and its 2025 revenue was KRW 56.7 billion, down about 6% year-on-year, comprising KRW 53.3 billion in product sales (94.0%), KRW 2.4 billion in merchandise sales (4.3%), and KRW 1.0 billion in other sales (1.7%). In September 2013 it signed an agreement with Catalyst Biosciences of the US, worth USD 1.75 million, to co-develop a subcutaneous hemophilia drug (through 2035, with worldwide rights excluding Korea), and since July 2019 it has been co-researching the Alzheimer's candidate ISU203 with Kyungpook National University.

Products & technology

  • AbcertinEnzyme replacement therapy
  • FabagalEnzyme replacement therapy
  • ClotinabAntibody therapy

Regulatory approvals

data.go.kr

5 Korean MFDS drug approvals · 2006–2015

  • MFDS drugPheburane Granule2015-08-21
    Drug · Prescription · Approval201505868
  • MFDS drugAbcertin Injection 400IU2015-05-08
    Drug · Prescription · Approval201502789
  • MFDS drugFabagal Injection2014-01-07
    Drug · Prescription · Approval201400051
  • MFDS drugAbcertin Injection 200IU2012-10-09
    Drug · Prescription · Approval201207109
  • MFDS drugClotinab Injection2006-12-28
    Drug · Prescription · Approval200611394

Clinical trials

data.go.kr

9 MFDS clinical trial authorisations · 2012–2025 (Phase 3 4 · Phase 2 3 · Phase 1 2)

  • Phase 3애브서틴주(이미글루세라제)2025-04-17
  • Phase 3클로티냅주(압식시맙)2019-07-18

    10 trial sites

  • Phase 1ISU1042017-08-17

    5 trial sites

  • Phase 1ISU3042017-03-27

    3 trial sites

  • Phase 3파바갈주(ISU303)2016-12-26

    9 trial sites

  • Phase 2클로티냅주(압식시맙)2013-03-29

    8 trial sites

  • Phase 2파바갈주(ISU303)2012-09-21

    4 trial sites

  • Phase 3애브서틴주(이미글루세라제)2012-05-23
  • Phase 2파바갈주(ISU303)2012-02-10

    5 trial sites

R&D and key agreements

Source: DART corporate disclosure

혈우병 신약(피하주사) · 혈우병(B형) · 임상2상 완료(남아프리카공화국), 한국 임상1상 완료(2013~2018) · Only subcutaneous hemophilia therapy in development, unlike existing IV treatments

ISU203 · 알츠하이머 · in vivo 효능검증 예비시험 공동연구중 · ASM inhibitor mechanism targeting amyloid-beta accumulation

ISU104 · 재발성/전이성 두경부암(대장암·유방암 적응증 확장 예정)

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Sources and updates

Company basics
Korea Exchange · DART
Business content
Compiled from disclosure filings
AI visibility
Measured 2026-08-13

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