Eutilex Co.,Ltd.
KOSDAQ-listed immuno-oncology biotech developing CAR-T and antibody therapeutics, including out-licensing candidate EU101 to China's Zhejiang Huahai Pharmaceutical.
As of 2026-10-08, Eutilex Co.,Ltd. has 26 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
Price
Change
Market cap
Business overview
Source: DART corporate disclosureFounded in 2015 and listed on KOSDAQ in 2018, Eutilex develops immuno-oncology therapies based on cell and gene therapy (CGT) and antibody therapeutics. Its 4th-generation armored CAR-T therapy EU307, which targets GPC3 and expresses IL-18, and its solid-tumor antibody therapy EU103, which converts tumor-associated M2 macrophages into M1 macrophages, are each in domestic Phase 1 trials, alongside its antibody therapy EU101 and antigen-specific T-cell therapy EU204. In September 2017, it out-licensed EU101 to China's Zhejiang Huahai Pharmaceutical Co., LTD. for a total deal value of KRW 9.659 billion (USD 8.5 million), and in March 2016 it in-licensed exclusive rights to immune cell therapy patents from the National Cancer Center for a total deal value of KRW 2.8 billion plus a separate 1.5% royalty.
Clinical trials
data.go.kr4 MFDS clinical trial authorisations · 2018–2023 (Phase 1 2 · Phase 1/2 1 · Phase 1/2a 1)
- Phase 1EU1032023-03-13
3 trial sites
- Phase 1EU3072023-02-15
4 trial sites
- Phase 1/2EU1012021-05-14
4 trial sites
- Phase 1/2a앱비앤티셀2018-09-17
9 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 1 · Unknown · 2023-08 · NCT05783570
Phase 1 · Unknown · 2023-08 · NCT05798026
Phase 1/2 · Unknown · 2021-05 · NCT04903873
Phase 1/2 · Unknown · 2018-12 · NCT03789617
R&D and key agreements
Source: DART corporate disclosureEU307 · 고형암(간암 등, GPC3 발현) · 국내 임상1상(IND 승인 2023.02) · 4th-generation armored CAR-T therapy expressing IL-18, targeting GPC3
EU103 · 고형암 · 국내 임상1상(IND 승인 2023.03) · Antibody therapy converting tumor-associated M2 macrophages to M1
EU101 · Antibody therapy binding a human T-cell activation stimulatory factor
EU204 · Antigen-specific T-cell therapy
Key disclosures
KRX KIND via OpenDARTShow 20 more events
Publications
PubMed · affiliation-matched- Immunogenicity of an Oil-in-Water Emulsion Containing Hafnia Alvei-Derived Lipopolysaccharide, with TLR4 and Dectin-2 Agonist Activity In Vitro.
Vaccines · 2026-06 · Hong RR, Lee EJ, Kwon JH 외 5
- Rhus Verniciflua Stokes Inhibits PD-1 Expression and Induces Anticancer Effects by Enhancing T Cell Function.
Integrative cancer therapies · 2025-01 · Kim S, Lee YK, Lee WJ 외 2
- Phase 1 trial of 4-1BB-based adoptive T-cell therapy targeting human telomerase reverse transcriptase in patients with advanced refractory solid tumors.
Cytotherapy · 2023-11 · Choi W, Lee Y, Choi BK 외 9
- 4-1BB-4-1BBL cis-interaction contributes to the survival of self-reactive CD8+ T cell.
Cellular & molecular immunology · 2023-09 · Cho E, Singh R, Han C 외 9
- Cross-Activation of Regulatory T Cells by Self Antigens Limits Self-Reactive and Activated CD8+ T Cell Responses.
International journal of molecular sciences · 2023-09 · Cho E, Han S, Eom HS 외 10
- Targeting 4-1BB and PD-L1 induces potent and durable antitumor immunity in B-cell lymphoma.
Frontiers in immunology · 2022-01 · Wang Y, Zhang X, Xu C 외 5
- Adoptive immunotherapy with transient anti-CD4 treatment enhances anti-tumor response by increasing IL-18Rαhi CD8+ T cells.
Nature communications · 2021-09 · Kim SH, Cho E, Kim YI 외 3
- IL7-Fc Enhances the Efficacy of Adoptive T Cell Therapy under Lymphopenic Conditions in a Murine Melanoma Model.
Cells · 2021-08 · Yu EM, Cho E, Singh R 외 7
- Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses.
Cellular & molecular immunology · 2021-08 · Kim SH, Singh R, Han C 외 10
- Ocular surface complications of local anticancer drugs for treatment of ocular tumors.
The ocular surface · 2021-01 · Moon J, Choi SH, Lee MJ 외 5
Show 16 more publications
- Polymorphic Region-Specific Antibody for Evaluation of Affinity-Associated Profile of Chimeric Antigen Receptor.
Molecular therapy oncolytics · 2020-06 · Han C, Choi BK, Kim SH 외 10
- Delayed IL-21 treatment preferentially expands peptide-specific CD8+ T cells by reducing bystander activation of T cells.
Immunotherapy · 2019-04 · Kim SH, Park SY, Lim MC 외 6
- The hyaluronic acid-rich node and duct system is a structure organized for innate immunity and mediates the local inflammation.
Cytokine · 2019-01 · Choi BK, Hwang SH, Kim YI 외 2
- Harnessing immune checkpoints for cancer therapy.
Immunotherapy · 2018-10 · Vinay DS, Kwon BS
- RELT negatively regulates the early phase of the T-cell response in mice.
European journal of immunology · 2018-10 · Choi BK, Kim SH, Kim YH 외 7
- Chimeric antigen receptor T-cell therapy for cancer: a basic research-oriented perspective.
Immunotherapy · 2018-03 · Han C, Kwon BS
- Cancer immunotherapy using tumor antigen-reactive T cells.
Immunotherapy · 2018-03 · Choi BK, Kim SH, Kim YH 외 1
- Myeloid-Derived Suppressor Cells Mediate Inflammation Resolution in Humans and Mice with Autoimmune Uveoretinitis.
Journal of immunology (Baltimore, Md. : 1950) · 2018-02 · Jeong HJ, Lee HJ, Ko JH 외 7
- Desensitized chimeric antigen receptor T cells selectively recognize target cells with enhanced antigen expression.
Nature communications · 2018-02 · Han C, Sim SJ, Kim SH 외 11
- Predictors of responses to immune checkpoint blockade in advanced melanoma.
Nature communications · 2017-09 · Jacquelot N, Roberti MP, Enot DP 외 47
- Mesenchymal stromal cells promote B-cell lymphoma in lacrimal glands by inducing immunosuppressive microenvironment.
Oncotarget · 2017-09 · Lee MJ, Park SY, Ko JH 외 6
- 4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8+ T cell proliferation.
Cellular & molecular immunology · 2017-09 · Choi BK, Lee DY, Lee DG 외 5
- Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFκB pathways in autophagy- and p62-dependent manners.
Oncotarget · 2017-06 · Ko JH, Yoon SO, Lee HJ 외 1
- Immunogenicity and immunomodulatory effects of the human chondrocytes, hChonJ.
BMC musculoskeletal disorders · 2017-05 · Lim CL, Lee YJ, Cho JH 외 4
- The repopulating cancer cells in melanoma are characterized by increased mitochondrial membrane potential.
Cancer letters · 2016-11 · Lee DG, Choi BK, Kim YH 외 4
- Extracellular stimulation of VSIG4/complement receptor Ig suppresses intracellular bacterial infection by inducing autophagy.
Autophagy · 2016-09 · Kim KH, Choi BK, Kim YH 외 4
Patents
KIPRIS · applicant-matchedPublished · 2025-01 · Application 1020250007536
TW · Published · 2024-07 · Application 113127139
PCT · Published · 2024-07 · Application PCT/KR2024/010497
Published · 2024-07 · Application 1020240095243
US · Published · 2024-03 · Application 18622113
Registered · 2023-12 · Application 1020230174892
PCT · Published · 2023-10 · Application PCT/KR2023/016397
Withdrawn · 2023-10 · Application 1020230141355
US · Published · 2023-06 · Application 18333096
PCT · Published · 2022-12 · Application PCT/KR2022/020065
Show 117 more patents
Rejected · 2022-12 · Application 1020220171906
PCT · Published · 2022-07 · Application PCT/KR2022/009887
PCT · Published · 2022-07 · Application PCT/KR2022/009890
Registered · 2022-07 · Application 1020220083925
Rejected · 2022-07 · Application 1020220083900
PCT · Published · 2022-06 · Application PCT/KR2022/008698
Registered · 2022-05 · Application 1020220066814
PCT · Published · 2022-04 · Application PCT/KR2022/005485
Withdrawn · 2022-04 · Application 1020220047056
PCT · Published · 2022-02 · Application PCT/KR2022/001708
Withdrawn · 2022-02 · Application 1020220014350
CN · Published · 2022-01 · Application 202280009724.5
EP · Published · 2022-01 · Application 22736677.0
PCT · Published · 2022-01 · Application PCT/IB2022/000009
Registered · 2022-01 · Application 1020237005801
Registered · 2022-01 · Application 1020227040417
CN · Published · 2021-12 · Application 202180083724.5
US · Published · 2021-12 · Application 18256999
EP · Published · 2021-12 · Application 21903911.2
PCT · Published · 2021-12 · Application PCT/KR2021/018795
PCT · Published · 2021-12 · Application PCT/KR2021/018799
Published · 2021-12 · Application 1020210176744
Published · 2021-12 · Application 1020210176964
PCT · Published · 2021-12 · Application PCT/KR2021/018229
CN · Published · 2021-09 · Application 202180061743.8
US · Registered · 2021-09 · Application 17469549
EP · Published · 2021-09 · Application 21866153.6
Published · 2021-09 · Application 1020237011158
US · Registered · 2021-08 · Application 17397559
PCT · Published · 2021-08 · Application PCT/IB2021/000543
Rejected · 2021-08 · Application 1020237008130
CN · Published · 2021-07 · Application 202180048794.7
US · Published · 2021-07 · Application 18004575
EP · Published · 2021-07 · Application 21837391.8
PCT · Published · 2021-07 · Application PCT/IB2021/056106
Rejected · 2021-07 · Application 1020237004667
US · Published · 2021-06 · Application 18008941
PCT · Published · 2021-06 · Application PCT/IB2021/054848
Abandoned · 2021-06 · Application 1020210072083
Rejected · 2021-04 · Application 1020210046244
Withdrawn · 2021-04 · Application 1020210045888
CN · Published · 2021-03 · Application 202180029132.5
US · Registered · 2021-03 · Application 17906718
US · Published · 2021-03 · Application 17906722
EP · Published · 2021-03 · Application 21771464.1
EP · Published · 2021-03 · Application 21771035.9
PCT · Published · 2021-03 · Application PCT/IB2021/052294
PCT · Published · 2021-03 · Application PCT/IB2021/052292
Registered · 2021-03 · Application 1020227035620
Published · 2021-03 · Application 1020257033533
Rejected · 2021-03 · Application 1020227035621
US · Registered · 2021-03 · Application 17188011
US · Published · 2021-02 · Application 17169093
US · Published · 2021-02 · Application 17169091
US · Registered · 2021-01 · Application 17158474
CN · Published · 2020-06 · Application 202080047355.X
CN · Published · 2020-06 · Application 202411914064.2
US · Published · 2020-06 · Application 17622503
EP · Published · 2020-06 · Application 20831651.3
PCT · Published · 2020-06 · Application PCT/IB2020/056097
Registered · 2020-06 · Application 1020227001944
US · Registered · 2020-04 · Application 16838887
US · Registered · 2020-02 · Application 16790299
PCT · Published · 2020-01 · Application PCT/KR2020/001376
US · Registered · 2019-12 · Application 16715695
US · Registered · 2019-12 · Application 16715462
US · Published · 2019-12 · Application 16715521
CN · Published · 2019-09 · Application 201980077997.1
EP · Published · 2019-09 · Application 19867865.8
PCT · Published · 2019-09 · Application PCT/US2019/053824
Registered · 2019-09 · Application 1020217012782
US · Published · 2019-09 · Application 16566451
CN · Published · 2019-08 · Application 201980067331.8
CN · Published · 2019-08 · Application 201980066897.9
CN · Published · 2019-08 · Application 201980066537.9
EP · Published · 2019-08 · Application 19847176.5
EP · Published · 2019-08 · Application 19847519.6
EP · Published · 2019-08 · Application 19848755.5
PCT · Published · 2019-08 · Application PCT/KR2019/010244
PCT · Published · 2019-08 · Application PCT/KR2019/010242
PCT · Published · 2019-08 · Application PCT/KR2019/010240
Registered · 2019-08 · Application 1020217007134
Rejected · 2019-08 · Application 1020217007133
Registered · 2019-08 · Application 1020217007135
Registered · 2019-05 · Application 1020190063716
CN · Published · 2019-04 · Application 201980026336.6
US · Published · 2019-04 · Application 17048492
EP · Published · 2019-04 · Application 19788111.3
PCT · Published · 2019-04 · Application PCT/KR2019/004349
US · Registered · 2019-03 · Application 16358636
US · Registered · 2019-01 · Application 16255690
US · Registered · 2018-11 · Application 16191381
Registered · 2018-04 · Application 1020180044411
US · Registered · 2018-03 · Application 15936209
CN · Published · 2018-02 · Application 201880026169.0
US · Published · 2018-02 · Application 16485598
EP · Published · 2018-02 · Application 18757730.9
PCT · Published · 2018-02 · Application PCT/IB2018/000227
Registered · 2018-02 · Application 1020197026919
CN · Published · 2018-02 · Application 201880003066.2
EP · Published · 2018-02 · Application 21152568.8
EP · Published · 2018-02 · Application 18751349.4
PCT · Published · 2018-02 · Application PCT/IB2018/000201
Withdrawn · 2018-02 · Application 1020197001731
US · Registered · 2018-01 · Application 15866042
CN · Published · 2018-01 · Application 201880005123.0
CN · Published · 2018-01 · Application 202011039658.5
US · Registered · 2018-01 · Application 15863526
EP · Published · 2018-01 · Application 21211128.0
EP · Registered · 2018-01 · Application 18736336.1
PCT · Published · 2018-01 · Application PCT/IB2018/000043
Registered · 2018-01 · Application 1020197015730
Registered · 2018-01 · Application 1020207006944
US · Registered · 2017-12 · Application 15829048
US · Registered · 2017-08 · Application 15691179
US · Registered · 2015-03 · Application 14639679
Expired · 2014-04 · Application 1020140051586
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Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
- Publications
- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
- Patents
- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
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- Measured 2026-10-01
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