Alteogen Inc.
KOSDAQ-listed biotech behind the Hybrozyme IV-to-SC platform and the Eyluxvi Eylea biosimilar.
As of 2026-10-10, Alteogen Inc. has 2 Korean MFDS drug approvals, 9 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Market cap
Business overview
Source: DART corporate disclosureFounded in 2008 and listed on KOSDAQ in 2014, Alteogen is a biotech company specializing in biobetters and biosimilars. It out-licenses platform technologies to global pharmaceutical companies including MSD, AstraZeneca, GSK, Daiichi Sankyo, and Sandoz, including Hybrozyme™ (hyaluronidase technology converting IV to SC formulations), NexP™ (long-acting biologics fusion technology), and NexMab™ (antibody-drug conjugate technology). Its core asset ALT-B4 (berahyaluronidase alfa) was commercialized as a standalone injection (Tergase Inj.) in 2024; its Herceptin biosimilar was out-licensed to Qilu Pharmaceutical of China and commercialized there in 2024, generating royalty income; and its Eylea biosimilar Eyluxvi® completed global Phase 3 trials in 2024 and received European marketing authorization in September 2025.
Products & technology
- ALT-B4 (berahyaluronidase alfa)Hyaluronidase enabling IV-to-SC formulation conversion
- Tergase Inj. (ALT-B4 standalone injection)Standalone hyaluronidase injection for pain and swelling relief
- Herceptin biosimilarAntibody biosimilar for breast cancer treatment
- Eyluxvi (Eylea biosimilar)Antibody biosimilar for ophthalmic disease treatment
Regulatory approvals
data.go.kr2 Korean MFDS drug approvals · 2024–2026
- MFDS drugEYZANFY Injection(Aflibercept)2026-05-14Drug · Prescription · Approval202601428
- MFDS drugTergase Injection(Berahyaluronidase alfa(Recombinant hyaluronidase))2024-07-05Drug · Prescription · Approval202401660
Clinical trials
data.go.kr4 MFDS clinical trial authorisations · 2017–2021 (Phase 1 3 · Phase 1/2a 1)
- Phase 1ALT-BB42021-09-15
4 trial sites
- Phase 1ALT-L92019-05-21
4 trial sites
- Phase 1/2aALT-P12017-07-11
3 trial sites
- Phase 1ALT-P72017-06-16
2 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 1 · Completed · 2022-01 · NCT05232175
Phase 1 · Completed · 2020-02 · NCT04058535
Phase 1 · Completed · 2018-01 · NCT03281824
Phase 1 · Completed · 2016-02 · NCT03242239
R&D and key agreements
Source: DART corporate disclosureNexP™ 융합기술 · 플랫폼 기술 · Long-acting biologics fusion technology
NexMab™ (ADC 기술) · 플랫폼 기술 · Next-generation antibody-drug conjugate technology
Key disclosures
KRX KIND via OpenDARTShow 10 more events
Publications
PubMed · affiliation-matched- Effect of berahyaluronidase alfa on subcutaneous absorption and local tolerability of ALT-P7, an antibody-drug conjugate in preclinical studies.
Journal of controlled release : official journal of the Controlled Release Society · 2026-08 · Jung W, Kim W, Lee EM 외 8
- The Safety, Tolerability, and Pharmacokinetics of ALT-BB4 (A Novel Recombinant Hyaluronidase): A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study in Healthy Volunteers.
Dermatology and therapy · 2025-11 · Lee JS, Kim W, Won CH 외 9
- Cryo-EM Structure of Human Hyaluronidase PH-20.
Proteins · 2025-05 · Im SB, Song HN, Jeong TK 외 4
- Toxicity of the recombinant human hyaluronidase ALT-BC4 on embryonic development.
Journal of animal science and technology · 2021-03 · Lee JH, Yoo M, Lee SM 외 3
- Role of the P2 residue of human alpha 1-antitrypsin in determining target protease specificity.
PloS one · 2017-01 · Chung HS, Kim JS, Lee SM 외 1
- Additional N-glycosylation in the N-terminal region of recombinant human alpha-1 antitrypsin enhances the circulatory half-life in Sprague-Dawley rats.
Glycoconjugate journal · 2016-04 · Chung HS, Kim JS, Lee SM 외 1
- Oxidation Protection in Metal-Binding Peptide Motif and Its Application to Antibody for Site-Selective Conjugation.
PloS one · 2016-01 · Chung HS, Lee S, Park SJ
- Novel AGLP-1 albumin fusion protein as a long-lasting agent for type 2 diabetes.
BMB reports · 2013-12 · Kim YM, Lee SM, Chung HS
- The N-terminal alanine-extended GLP-1/IgG-Fc fusion protein confers resistance to DPP-IV and reduces serum glucose level in db/db mice.
Regulatory peptides · 2011-10 · Chung HS, Oh JY, Yoo SB 외 2
Patents
KIPRIS · applicant-matchedPublished · 2025-09 · Application 1020250139407
PCT · Published · 2025-09 · Application PCT/KR2025/015130
US · Published · 2025-06 · Application 19231008
PCT · Published · 2025-05 · Application PCT/KR2025/007364
Published · 2024-11 · Application 1020240170525
US · Published · 2024-11 · Application 18940159
US · Published · 2024-11 · Application 18940064
Published · 2024-07 · Application 1020240087254
CN · Published · 2024-03 · Application 202480021197.9
Published · 2024-03 · Application 1020257031675
Show 150 more patents
EP · Published · 2024-03 · Application 24775219.9
PCT · Published · 2024-03 · Application PCT/KR2024/003567
Registered · 2024-03 · Application 1020240036308
PCT · Published · 2023-08 · Application PCT/KR2023/012247
CN · Published · 2023-06 · Application 202380015218.1
TW · Registered · 2023-06 · Application 113149446
TW · Registered · 2023-06 · Application 112123526
Registered · 2023-06 · Application 1020230079623
US · Published · 2023-06 · Application 18721629
EP · Published · 2023-06 · Application 23827518.4
PCT · Published · 2023-06 · Application PCT/KR2023/008621
Withdrawn · 2023-06 · Application 1020230070948
CN · Published · 2022-10 · Application 202280081110.8
Published · 2022-10 · Application 1020220141287
US · Published · 2022-10 · Application 18705496
EP · Published · 2022-10 · Application 22887701.5
PCT · Published · 2022-10 · Application PCT/KR2022/016709
CN · Published · 2022-10 · Application 202280083603.5
Published · 2022-10 · Application 1020220134388
US · Published · 2022-10 · Application 18702881
EP · Published · 2022-10 · Application 22883963.5
PCT · Published · 2022-10 · Application PCT/KR2022/015837
Rejected · 2022-09 · Application 1020220114104
US · Published · 2022-07 · Application 17859466
US · Published · 2022-05 · Application 17744575
TW · Registered · 2022-04 · Application 112131180
TW · Registered · 2022-04 · Application 111114160
Expired · 2022-04 · Application 1020220045946
EP · Published · 2022-04 · Application 22788457.4
PCT · Published · 2022-04 · Application PCT/KR2022/005379
US · Registered · 2021-12 · Application 17551103
TW · Registered · 2021-08 · Application 110130965
CN · Published · 2021-08 · Application 202180030097.9
CN · Published · 2021-08 · Application 202510513013.7
Registered · 2021-08 · Application 1020210103530
US · Registered · 2021-08 · Application 17907538
EP · Published · 2021-08 · Application 21853474.1
PCT · Published · 2021-08 · Application PCT/KR2021/010368
CN · Published · 2021-01 · Application 202511402467.3
CN · Published · 2021-01 · Application 202510864007.6
CN · Published · 2021-01 · Application 202511194122.3
CN · Published · 2021-01 · Application 202180003323.4
CN · Published · 2021-01 · Application 202511444719.9
TW · Registered · 2021-01 · Application 110102662
TW · Registered · 2021-01 · Application 111136059
TW · Published · 2021-01 · Application 114147428
Published · 2021-01 · Application 1020257013439
Registered · 2021-01 · Application 1020227013211
US · Registered · 2021-01 · Application 17608729
EP · Published · 2021-01 · Application 21743774.8
PCT · Published · 2021-01 · Application PCT/KR2021/000943
Withdrawn · 2020-11 · Application 1020200156910
TW · Registered · 2020-06 · Application 111128188
TW · Published · 2020-06 · Application 111145281
TW · Registered · 2020-06 · Application 111101316
TW · Registered · 2020-06 · Application 109119328
CN · Published · 2020-03 · Application 202310758097.1
CN · Published · 2020-03 · Application 202510217756.X
CN · Published · 2020-03 · Application 202510219592.4
CN · Published · 2020-03 · Application 202310416462.0
CN · Published · 2020-03 · Application 202080003052.8
CN · Published · 2020-03 · Application 202510225530.4
CN · Published · 2020-03 · Application 202510236310.1
Published · 2020-03 · Application 1020237007559
Registered · 2020-03 · Application 1020207030248
Registered · 2020-03 · Application 1020227016935
US · Registered · 2020-03 · Application 17052952
EP · Published · 2020-03 · Application 24185844.8
EP · Published · 2020-03 · Application 20776465.5
PCT · Published · 2020-03 · Application PCT/KR2020/003975
CN · Published · 2019-07 · Application 202411131157.8
CN · Published · 2019-07 · Application 202411133487.0
CN · Published · 2019-07 · Application 201980023392.4
CN · Published · 2019-07 · Application 202411127100.0
CN · Published · 2019-07 · Application 202411131388.9
Published · 2019-07 · Application 1020257002900
Abandoned · 2019-07 · Application 1020207024813
Registered · 2019-07 · Application 1020207002955
US · Registered · 2019-07 · Application 16628258
EP · Registered · 2019-07 · Application 19827585.1
PCT · Published · 2019-07 · Application PCT/KR2019/009215
PCT · Published · 2019-06 · Application PCT/KR2019/007032
CN · Published · 2019-03 · Application 201980027952.3
US · Registered · 2019-03 · Application 16980074
EP · Published · 2019-03 · Application 19767280.1
PCT · Published · 2019-03 · Application PCT/KR2019/002911
CN · Published · 2018-12 · Application 201880083338.4
US · Registered · 2018-12 · Application 16954902
EP · Published · 2018-12 · Application 18890773.7
PCT · Published · 2018-12 · Application PCT/KR2018/016311
Registered · 2018-11 · Application 1020180147700
Registered · 2018-06 · Application 1020180069221
Registered · 2018-03 · Application 1020180029762
Rejected · 2017-12 · Application 1020170166663
CN · Published · 2017-03 · Application 202210306570.8
CN · Published · 2017-03 · Application 201780027885.6
Registered · 2017-03 · Application 1020170040472
US · Registered · 2017-03 · Application 16088804
EP · Registered · 2017-03 · Application 17779307.2
EP · Published · 2017-03 · Application 22191369.2
PCT · Published · 2017-03 · Application PCT/KR2017/003508
US · Published · 2016-12 · Application 15393365
PCT · Published · 2016-10 · Application PCT/KR2016/012009
CN · Published · 2016-10 · Application 201680059726.X
CN · Published · 2016-10 · Application 202210985550.8
US · Registered · 2016-10 · Application 15767806
EP · Published · 2016-10 · Application 22186197.4
EP · Registered · 2016-10 · Application 16855776.7
PCT · Published · 2016-10 · Application PCT/KR2016/011561
Registered · 2016-10 · Application 1020160132633
CN · Published · 2016-06 · Application 201680036177.4
US · Registered · 2016-06 · Application 15190378
EP · Published · 2016-06 · Application 24210101.2
EP · Registered · 2016-06 · Application 20195634.9
EP · Registered · 2016-06 · Application 16814702.3
PCT · Published · 2016-06 · Application PCT/KR2016/006679
Registered · 2016-06 · Application 1020160078234
Registered · 2015-10 · Application 1020150149511
Registered · 2015-10 · Application 1020150144752
PCT · Published · 2015-10 · Application PCT/KR2015/010933
US · Registered · 2015-10 · Application 14884312
Withdrawn · 2015-06 · Application 1020150078850
PCT · Published · 2013-11 · Application PCT/KR2013/010630
CN · Published · 2013-10 · Application 201380065765
Expired · 2013-10 · Application 1020130126295
US · Registered · 2013-10 · Application 14439644
EP · Published · 2013-10 · Application 13857947.9
PCT · Published · 2013-10 · Application PCT/KR2013/009474
US · Registered · 2013-06 · Application 14406192
EP · Registered · 2013-06 · Application 13800310.8
PCT · Published · 2013-06 · Application PCT/KR2013/004985
JP · Registered · 2013-06 · Application 27515950
Expired · 2013-05 · Application 1020130063053
Registered · 2013-02 · Application 1020130018955
US · Registered · 2013-02 · Application 14380068
EP · Registered · 2013-02 · Application 13752075.5
PCT · Published · 2013-02 · Application PCT/KR2013/001417
JP · Registered · 2013-02 · Application 26558681
Expired · 2012-11 · Application 1020120132549
EP · Registered · 2012-08 · Application 12831806.0
PCT · Published · 2012-08 · Application PCT/KR2012/006441
JP · Registered · 2012-08 · Application 26530581
Registered · 2012-06 · Application 1020120060641
Registered · 2012-06 · Application 1020120058998
Expired · 2010-05 · Application 1020100044288
PCT · Published · 2010-05 · Application PCT/KR2010/002998
Registered · 2010-04 · Application 1020100037496
EP · Registered · 2010-04 · Application 10767304.8
PCT · Published · 2010-04 · Application PCT/KR2010/002520
JP · Registered · 2010-04 · Application 24505833
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How to connect (MCP)Companies in the same categoryBiotech & Drug Discovery
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A diversified SK group company operating eco-friendly chemical materials alongside pharmaceutical products like Joins and vaccines through subsidiary SK Bioscience.
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KOSDAQ-listed antibody biotech developing the next-generation immuno-oncology candidate Multi-AbKine on its fully human antibody library Ymax®-ABL.
A holding company overseeing 54 affiliates including its main biopharmaceutical subsidiary GC, with no direct product manufacturing of its own.
Founded in 2015 and listed on KOSPI in 2021, Prestige BioPharma develops antibody biosimilars and novel antibody drugs including Tuznue.
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SillaJen, Inc., founded in 2006 and listed on KOSDAQ in 2016, develops the oncolytic virus immunotherapy Pexa-Vec.
A vaccine specialist developing in-house products such as SKYCellflu and SKYZoster while also serving as CDMO for AstraZeneca and Novavax.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
- Publications
- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
- Patents
- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
- AI visibility
- Measured 2026-10-01
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