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Biotech & Drug DiscoveryKOSDAQ 174900Orphan Drug1 approvals1 trials

Founded in 2010 and KOSDAQ-listed in 2017, AbClon Inc. develops the HER2-targeting antibody AC101 (HLX22) via its NEST discovery platform.

As of 2026-10-10, AbClon Inc. has 9 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).

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Business overview

Source: DART corporate disclosure

Founded in 2010 by Korean and Swedish scientist groups and listed on KOSDAQ in 2017, AbClon Inc. is a biotech venture developing antibody therapeutics. The company operates the NEST antibody discovery platform and the AffiMab bispecific antibody platform, with its lead pipeline being the HER2-targeting antibody AC101 (HLX22). AbClon licensed AC101's China rights to Shanghai Henlius Biotech for USD 16.5 million (about KRW 18.8 billion) in 2016, transferred full global rights in 2018, and completed first-patient dosing in a global Phase 3 trial for metastatic gastric cancer in the US in July 2025.

Products & technology

  • AC101 (HLX22)HER2-targeting antibody for HER2-positive gastric/GEJ cancer and breast cancer

Regulatory approvals

1 Orphan Drug designations · 2025

  • OrphanNespe-cel (자가혈액유래 CD19 표적 CAR-T 세포, AT101)2025-09-17
    Orphan Drug designation · in development20250156335

Clinical trials

data.go.kr

1 MFDS clinical trial authorisations · 2021 (Phase 1/2 1)

  • Phase 1/2AT1012021-12-28

    7 trial sites

Global clinical trials

ClinicalTrials.gov · sponsor-matched

R&D and key agreements

Source: DART corporate disclosure

AC101 (HLX22) · HER2 양성 위암·위식도접합부암(G/GEJ) · 글로벌 임상 3상(미국) · FDA approved Phase 3 IND (May 2024); Japan approved Phase 3 for metastatic gastric cancer (Oct 2024); first patient dosed in US Phase 3 (Jul 2025).

AC101 (HLX22) · HER2 저발현 유방암(엔허투 병용) · 임상 2상 · First patient dosed Apr 2025 in Phase 2 combining AC101 with Enhertu for HER2-low breast cancer.

Key disclosures

KRX KIND via OpenDART

Publications

PubMed · affiliation-matched

Patents

KIPRIS · applicant-matched
Show 76 more patents

AI reads

MAA server logs · IP-verified
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Sources and updates

Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.

Company basics
Korea Exchange · DART
Business content
Compiled from disclosure filings
Approvals & clinical trials
Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
Key disclosures
KRX KIND via OpenDART exchange filings — updated daily
Global clinical trials
ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
Financials
DART corporate disclosure filings — annual
Publications
PubMed (US National Library of Medicine) — affiliation-matched, updated daily
Patents
KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
AI reads
Our server logs, IP-verified every 6 hours
AI visibility
Measured 2026-10-01

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