AbClon Inc.
Founded in 2010 and KOSDAQ-listed in 2017, AbClon Inc. develops the HER2-targeting antibody AC101 (HLX22) via its NEST discovery platform.
As of 2026-10-10, AbClon Inc. has 9 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
Price
Change
Market cap
Business overview
Source: DART corporate disclosureFounded in 2010 by Korean and Swedish scientist groups and listed on KOSDAQ in 2017, AbClon Inc. is a biotech venture developing antibody therapeutics. The company operates the NEST antibody discovery platform and the AffiMab bispecific antibody platform, with its lead pipeline being the HER2-targeting antibody AC101 (HLX22). AbClon licensed AC101's China rights to Shanghai Henlius Biotech for USD 16.5 million (about KRW 18.8 billion) in 2016, transferred full global rights in 2018, and completed first-patient dosing in a global Phase 3 trial for metastatic gastric cancer in the US in July 2025.
Products & technology
- AC101 (HLX22)HER2-targeting antibody for HER2-positive gastric/GEJ cancer and breast cancer
Regulatory approvals
1 Orphan Drug designations · 2025
- OrphanNespe-cel (자가혈액유래 CD19 표적 CAR-T 세포, AT101)2025-09-17Orphan Drug designation · in development20250156335
Clinical trials
data.go.kr1 MFDS clinical trial authorisations · 2021 (Phase 1/2 1)
- Phase 1/2AT1012021-12-28
7 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 1/2 · Recruiting · 2022-03 · NCT05338931
R&D and key agreements
Source: DART corporate disclosureAC101 (HLX22) · HER2 양성 위암·위식도접합부암(G/GEJ) · 글로벌 임상 3상(미국) · FDA approved Phase 3 IND (May 2024); Japan approved Phase 3 for metastatic gastric cancer (Oct 2024); first patient dosed in US Phase 3 (Jul 2025).
AC101 (HLX22) · HER2 저발현 유방암(엔허투 병용) · 임상 2상 · First patient dosed Apr 2025 in Phase 2 combining AC101 with Enhertu for HER2-low breast cancer.
Key disclosures
KRX KIND via OpenDARTShow 11 more events
Publications
PubMed · affiliation-matched- The BTLA-HVEM axis restricts CAR T cell efficacy in cancer.
Nature immunology · 2024-06 · Guruprasad P, Carturan A, Zhang Y 외 35
- Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study.
Molecular cancer · 2023-12 · Zhang Y, Patel RP, Kim KH 외 35
- Construction of Rabbit Immune Antibody Libraries.
Methods in molecular biology (Clifton, N.J.) · 2023-01 · Nguyen TTH, Lee JS, Shim H
- Bispecific Antibody Molecule Inhibits Tumor Cell Proliferation More Efficiently Than the Two-Molecule Combination.
Drugs in R&D · 2021-06 · Volk AL, Mebrahtu A, Ko BK 외 7
- Construction of Rabbit Immune Antibody Libraries.
Methods in molecular biology (Clifton, N.J.) · 2018-01 · Nguyen TTH, Lee JS, Shim H
- Establishment of a Patient-derived Xenograft for Development of Personalized HER2-targeting Therapy in Gastric Cancer.
Anticancer research · 2018-01 · Shin SH, Park SS, Ju EJ 외 12
- Affibody molecules as engineered protein drugs.
Experimental & molecular medicine · 2017-03 · Frejd FY, Kim KT
- Combination of novel HER2-targeting antibody 1E11 with trastuzumab shows synergistic antitumor activity in HER2-positive gastric cancer.
Molecular oncology · 2015-02 · Ko BK, Lee SY, Lee YH 외 8
- Affinity Maturation of Monoclonal Antibody 1E11 by Targeted Randomization in CDR3 Regions Optimizes Therapeutic Antibody Targeting of HER2-Positive Gastric Cancer.
PloS one · 2015-01 · Ko BK, Choi S, Cui LG 외 5
Patents
KIPRIS · applicant-matchedCN · Published · 2024-04 · Application 202480033016.4
PCT · Published · 2024-04 · Application PCT/KR2024/005653
Published · 2024-04 · Application 1020257038515
EP · Published · 2024-04 · Application 24807399.1
CN · Published · 2024-04 · Application 202480018271.1
PCT · Published · 2024-04 · Application PCT/KR2024/005598
EP · Published · 2024-04 · Application 24807397.5
Published · 2024-04 · Application 1020240054991
US · Published · 2023-05 · Application 18198937
CN · Published · 2023-02 · Application 202380026867.1
Show 76 more patents
PCT · Published · 2023-02 · Application PCT/KR2023/002676
US · Published · 2023-02 · Application 18845226
EP · Published · 2023-02 · Application 23767060.9
Registered · 2023-02 · Application 1020230015852
CN · Published · 2022-12 · Application 202280102812.X
PCT · Published · 2022-12 · Application PCT/KR2022/021735
US · Published · 2022-12 · Application 19140815
EP · Published · 2022-12 · Application 22970280.8
US · Registered · 2022-12 · Application 18075648
Registered · 2022-09 · Application 1020220113082
Registered · 2021-11 · Application 1020210157117
PCT · Published · 2021-06 · Application PCT/KR2021/008023
PCT · Published · 2021-05 · Application PCT/KR2021/006361
Withdrawn · 2021-05 · Application 1020227045034
EP · Published · 2021-05 · Application 21809551.1
Registered · 2021-05 · Application 1020210058341
CN · Published · 2021-04 · Application 202180001956.1
US · Registered · 2021-04 · Application 17424970
EP · Published · 2021-04 · Application 21743362.2
PCT · Published · 2021-04 · Application PCT/KR2021/004793
Registered · 2020-07 · Application 1020200081179
Registered · 2020-04 · Application 1020200047025
CN · Published · 2019-04 · Application 201980026597.8
PCT · Published · 2019-04 · Application PCT/KR2019/004720
Registered · 2019-04 · Application 1020190045743
US · Registered · 2019-04 · Application 17048739
EP · Published · 2019-04 · Application 19787870.5
CN · Published · 2018-12 · Application 201880083127.0
Registered · 2018-12 · Application 1020180167818
US · Registered · 2018-12 · Application 16956807
EP · Registered · 2018-12 · Application 18892983.0
PCT · Published · 2018-12 · Application PCT/KR2018/016515
JP · Published · 2018-12 · Application 32534930
CN · Published · 2018-12 · Application 201880079137.7
Registered · 2018-12 · Application 1020180156433
US · Registered · 2018-12 · Application 16768412
EP · Published · 2018-12 · Application 18886531.5
PCT · Published · 2018-12 · Application PCT/KR2018/015445
PCT · Published · 2018-11 · Application PCT/KR2018/013928
Registered · 2018-11 · Application 1020180140251
Registered · 2018-07 · Application 1020180077947
CN · Published · 2018-04 · Application 201880026193.4
US · Registered · 2018-04 · Application 16606402
EP · Registered · 2018-04 · Application 18787034.0
PCT · Published · 2018-04 · Application PCT/KR2018/004516
PCT · Published · 2017-08 · Application PCT/KR2017/009311
JP · Registered · 2017-07 · Application 29132833
Registered · 2017-04 · Application 1020170049732
CN · Published · 2017-04 · Application 201780023274.4
US · Registered · 2017-04 · Application 16093486
EP · Registered · 2017-04 · Application 17782617.9
PCT · Published · 2017-04 · Application PCT/KR2017/003827
JP · Registered · 2017-04 · Application 30554349
Registered · 2017-04 · Application 1020170046881
PCT · Published · 2016-12 · Application PCT/KR2016/014676
US · Registered · 2016-11 · Application 15780046
EP · Registered · 2016-11 · Application 16870984.8
PCT · Published · 2016-11 · Application PCT/KR2016/013735
Rejected · 2016-08 · Application 1020160109988
Withdrawn · 2016-02 · Application 1020160019353
Registered · 2015-12 · Application 1020150179409
Registered · 2015-11 · Application 1020150168859
Withdrawn · 2015-07 · Application 1020150104445
CN · Published · 2015-06 · Application 201580039788.X
Registered · 2015-06 · Application 1020157018910
US · Registered · 2015-06 · Application 15317633
EP · Registered · 2015-06 · Application 15731002.0
PCT · Published · 2015-06 · Application PCT/EP2015/063364
Registered · 2014-12 · Application 1020140195243
Registered · 2014-08 · Application 1020140109642
CN · Published · 2014-05 · Application 201480024152
US · Registered · 2014-05 · Application 14781968
EP · Registered · 2014-05 · Application 14798440.5
PCT · Published · 2014-05 · Application PCT/KR2014/004317
JP · Registered · 2014-05 · Application 28508909
Registered · 2014-05 · Application 1020140057321
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Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
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- Measured 2026-10-01
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