Shaperon Inc.
Founded in 2008 and KOSDAQ-listed in 2022, Shaperon runs a GPCR19-targeted inflammasome inhibitor platform and a nanomab antibody platform.
As of 2026-10-10, Shaperon Inc. has 15 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
Price
Change
Market cap
Business overview
Source: DART corporate disclosureShaperon Inc. was founded in 2008 and listed on KOSDAQ in 2022, operating a GPCR19-targeted inflammasome inhibitor platform and a nanomab antibody development platform. Its lead pipeline includes NuSepin, a COVID-19 pneumonia treatment, alongside candidates for atopic dermatitis and Alzheimer's dementia. NuSepin completed a Phase 2 trial at five centers in Romania and a multinational Phase 2b trial backed by KRW 9.1 billion from the Korea Drug Development Fund (KDDF); the atopic dermatitis candidate received FDA IND approval in September 2023 and is in Phase 2b, the Alzheimer's candidate is in domestic Phase 1, and the company has completed two technology transfer deals.
Products & technology
- NuSepinCOVID-19 pneumonia and cardiopulmonary bypass-induced respiratory failure treatment
Clinical trials
data.go.kr6 MFDS clinical trial authorisations · 2012–2025 (Phase 1 3 · Phase 2 2 · Phase 2b/3 1)
- Phase 2HY2092025-02-04
4 trial sites
- Phase 2b/3HY209주2022-01-11
17 trial sites
- Phase 2HY2092020-06-19
5 trial sites
- Phase 1HY209주2019-05-13
2 trial sites
- Phase 1HY-209겔2016-12-12
1 trial site
- Phase 1HY-209 주사제2012-11-23
1 trial site
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 2 · Completed · 2024-03 · NCT06024499
Phase 2/3 · Unknown · 2022-04 · NCT05352347
Phase 2 · Completed · 2020-09 · NCT04565379
Phase 2 · Completed · 2020-08 · NCT04530643
Phase 1 · Completed · 2019-12 · NCT04255979
Phase 1 · Completed · 2018-01 · NCT03492398
R&D and key agreements
Source: DART corporate disclosureNuSepin · COVID-19 폐렴 · 임상2상 완료(루마니아 5개 센터, EMA승인, 2021), 다국적 임상2b상 완료 · Multinational Phase 2b trial completed with KRW 9.1bn KDDF funding
아토피 · FDA IND 승인(2023.09), 임상2b상 진행중 · FDA IND approval for atopic dermatitis candidate
알츠하이머 치매 · 국내 임상1상 진행중 · Domestic Phase 1 trial for Alzheimer's dementia candidate
Key disclosures
KRX KIND via OpenDARTShow 4 more events
Publications
PubMed · affiliation-matched- Correction: Nanobody engineering for enhanced-sensitivity rapid COVID-19 tests.
Nanoscale · 2026-01 · Jeong E, Oh SY, Son SU 외 13
- Nanobody engineering for enhanced-sensitivity rapid COVID-19 tests.
Nanoscale · 2025-10 · Jeong E, Oh SY, Son SU 외 13
- Corrigendum to "H1N1 nanobody development and therapeutic efficacy verification in H1N1-challenged mice" [Biomed. Pharmacother. 176 (2024) 116781].
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025-07 · Hwang J, Jang IY, Bae E 외 16
- Safety, Tolerability, and Pharmacokinetics of Single and Multiple Topical Applications of Sodium Taurodeoxycholate, a Treatment for Atopic Dermatitis.
Clinical and translational science · 2025-05 · Won H, Jeon I, Cho JY 외 2
- A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibitor, in patients with mild to moderate atopic dermatitis: a proof-of-concept study with Post-hoc biomarker analysis.
Frontiers in immunology · 2025-01 · Baek GH, Kim BR, Shin JW 외 14
- HIFU-CCL19/21 Axis Enhances Dendritic Cell Vaccine Efficacy in the Tumor Microenvironment.
Pharmaceutics · 2025-01 · Baek BS, Park H, Choi JW 외 2
- Oral Administration of Taurodeoxycholate, A GPCR19 Agonist, Effectively Ameliorates Atopic Dermatitis in A Mouse Model.
Experimental dermatology · 2024-10 · Ghaderpour A, Jeong JY, Koh YJ 외 1
- Dendritic cells pulsed with penetratin-OLFM4 inhibit the growth and metastasis of melanoma in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024-08 · Baek BS, Park H, Choi JW 외 3
- ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP.
Apoptosis : an international journal on programmed cell death · 2024-08 · Abbas R, Hartmann O, Asiss DT 외 7
- H1N1 nanobody development and therapeutic efficacy verification in H1N1-challenged mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024-07 · Hwang J, Jang IY, Bae E 외 16
Show 5 more publications
- Safety, Tolerability and Pharmacokinetics of Intravenous Sodium Taurodeoxycholate, HY209, a GPCR19 Agonist Inhibiting Inflammasomal Activation.
Drug design, development and therapy · 2024-01 · Chung WK, Jeon I, Jang IJ 외 3
- Myeloid-derived suppressor cells in pleural effusion as a diagnostic marker for early discrimination of pulmonary tuberculosis from pneumonia.
Frontiers in immunology · 2024-01 · Kim ES, Islam J, Lee HJ 외 5
- Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer's disease.
Experimental & molecular medicine · 2023-10 · Kim MY, Kim MJ, Lee C 외 7
- Taurodeoxycholate, a GPCR19 agonist, ameliorates atopic dermatitis in Balb/c mice.
European journal of immunology · 2023-05 · Ghaderpour A, Jeong JY, Kim YH 외 5
- GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease.
Frontiers in immunology · 2022-01 · Islam J, Cho JA, Kim JY 외 12
Patents
KIPRIS · applicant-matchedUS · Published · 2024-11 · Application 18951146
US · Published · 2024-10 · Application 18906683
PCT · Published · 2024-07 · Application PCT/KR2024/010771
Registered · 2024-07 · Application 1020240098310
PCT · Published · 2024-05 · Application PCT/KR2024/095872
Published · 2023-12 · Application 1020230195126
Published · 2023-11 · Application 1020230162813
EP · Published · 2023-11 · Application 23890943.6
PCT · Published · 2023-11 · Application PCT/IB2023/000703
Published · 2023-11 · Application 1020257017116
Show 67 more patents
Withdrawn · 2023-05 · Application 1020230069597
EP · Published · 2023-05 · Application 23807931.3
PCT · Published · 2023-05 · Application PCT/KR2023/006794
Rejected · 2023-05 · Application 1020230064573
EP · Published · 2023-04 · Application 23785022.7
PCT · Published · 2023-04 · Application PCT/KR2023/004665
Registered · 2023-04 · Application 1020230045518
Withdrawn · 2022-11 · Application 1020220152832
US · Published · 2022-10 · Application 18708357
EP · Published · 2022-10 · Application 22893086.3
PCT · Published · 2022-10 · Application PCT/KR2022/016721
Rejected · 2022-10 · Application 1020220129880
PCT · Published · 2022-09 · Application PCT/KR2022/014362
PCT · Published · 2022-09 · Application PCT/KR2022/014366
Rejected · 2022-09 · Application 1020220121781
Rejected · 2022-09 · Application 1020220121782
US · Published · 2022-09 · Application 18692366
US · Published · 2022-09 · Application 18694190
EP · Published · 2022-09 · Application 22870303.9
EP · Published · 2022-09 · Application 22873139.4
PCT · Published · 2022-09 · Application PCT/KR2022/013781
PCT · Published · 2022-09 · Application PCT/KR2022/013768
PCT · Published · 2022-09 · Application PCT/KR2022/013779
US · Published · 2022-07 · Application 18292654
EP · Published · 2022-07 · Application 22849867.1
PCT · Published · 2022-07 · Application PCT/KR2022/010998
Registered · 2022-07 · Application 1020220092810
US · Published · 2022-05 · Application 18561881
EP · Published · 2022-05 · Application 22804943.3
PCT · Published · 2022-05 · Application PCT/KR2022/007007
Registered · 2022-05 · Application 1020220059884
US · Published · 2022-02 · Application 18277914
US · Published · 2022-02 · Application 18277931
US · Published · 2022-02 · Application 18277926
EP · Published · 2022-02 · Application 22756591.8
EP · Published · 2022-02 · Application 22756592.6
EP · Published · 2022-02 · Application 22756590.0
PCT · Published · 2022-02 · Application PCT/KR2022/002530
PCT · Published · 2022-02 · Application PCT/KR2022/002529
PCT · Published · 2022-02 · Application PCT/KR2022/002527
Registered · 2022-02 · Application 1020220022524
Registered · 2022-02 · Application 1020220022523
Registered · 2022-02 · Application 1020220022525
PCT · Published · 2021-11 · Application PCT/KR2021/095101
Rejected · 2021-11 · Application 1020210154228
Registered · 2021-11 · Application 1020210152864
Registered · 2021-09 · Application 1020210126676
Registered · 2021-09 · Application 1020210122994
Rejected · 2021-09 · Application 1020210122993
US · Published · 2021-08 · Application 18026888
US · Published · 2021-08 · Application 18027027
EP · Published · 2021-08 · Application 21869571.6
PCT · Published · 2021-08 · Application PCT/KR2021/011234
PCT · Published · 2021-08 · Application PCT/KR2021/011232
PCT · Published · 2021-08 · Application PCT/KR2021/011231
Withdrawn · 2021-08 · Application 1020237005250
Withdrawn · 2021-08 · Application 1020237005249
Registered · 2021-08 · Application 1020237005251
US · Published · 2020-01 · Application 17284305
EP · Registered · 2020-01 · Application 20745833.2
Expired · 2019-01 · Application 1020190008527
US · Registered · 2017-03 · Application 15461086
Rejected · 2015-09 · Application 1020150124985
Registered · 2014-09 · Application 1020140125691
EP · Registered · 2014-03 · Application 14841209.1
Registered · 2013-08 · Application 1020130100813
EP · Registered · 2008-05 · Application 13169636.1
AI reads
MAA server logs · IP-verifiedPulled records become part of each AI's index and keep feeding its answers. When an AI cites from that index, nothing reaches our server — so actual citations are uncounted here and exceed this number.
Times an AI needed something not yet in its index and fetched this page fresh while answering. Citations served from the index leave no trace here.
Collected as raw material for future answers.
Queries from users who connected this index to their own AI.
- OpenAIChatGPT-Userlive1
- OpenAIOAI-SearchBot36
- PerplexityPerplexityBot2
- AnthropicClaudeBot2
- MicrosoftBingbot1
- GoogleGoogleOther1
Measured since Aug 27, 2026 · 5 AI engines · last read Oct 9, 2026
User-agent strings can be forged, so we do not count them at face value. We count only requests matched against vendor-published IP ranges, or confirmed by forward-verified reverse DNS. MCP queries are actual calls to this index's tool endpoint.
Connect this company index directly to your AI
Connect it to ChatGPT or Claude, and your AI queries the full record — profiles, financials, stock data, regulatory approvals, clinical trials, publications and patents — for Shaperon Inc. and every listed Korean medical, bio and AI company.
How to connect (MCP)Companies in the same categoryBiotech & Drug Discovery
KOSDAQ-listed integrated security company behind the V3 antivirus and AhnLab TrusGuard and XDR solutions.
Drug delivery system company behind the long-acting injectable platform IVL-DrugFluidic and the LNP delivery platform IVL-GeneFluidic.
Organoid-based biotech founded 2018, KOSDAQ-listed 2025, developing the ATORM-C regenerative therapeutic and ODISEI evaluation solution.
EDGC, a Korea-US joint venture of Eone Medical Foundation and Diagnomics, offers the NIPT service NICE and liquid biopsy OncoCatch.
A diversified SK group company operating eco-friendly chemical materials alongside pharmaceutical products like Joins and vaccines through subsidiary SK Bioscience.
Genomics and drug developer behind the osteoarthritis drug Acelex and the AI-driven healthcare platform Invites Loop.
KOSDAQ-listed antibody biotech developing the next-generation immuno-oncology candidate Multi-AbKine on its fully human antibody library Ymax®-ABL.
A holding company overseeing 54 affiliates including its main biopharmaceutical subsidiary GC, with no direct product manufacturing of its own.
Founded in 2015 and listed on KOSPI in 2021, Prestige BioPharma develops antibody biosimilars and novel antibody drugs including Tuznue.
KOSDAQ-listed biotech company developing molecular diagnostics with proprietary C-Tag technology and the NeoPlex product line.
SillaJen, Inc., founded in 2006 and listed on KOSDAQ in 2016, develops the oncolytic virus immunotherapy Pexa-Vec.
A vaccine specialist developing in-house products such as SKYCellflu and SKYZoster while also serving as CDMO for AstraZeneca and Novavax.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
- Publications
- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
- Patents
- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
- AI visibility
- Measured 2026-10-01
This page is compiled from public sources without the company's involvement. If anything is inaccurate or incomplete, please let us know. Materials provided by the company are labelled as such.
Request a correction or addition