ProGen, Co,, LTD.
KONEX-listed biotech venture developing new drug candidates with its multi-target fusion protein platform NTIG®
As of 2026-10-10, ProGen, Co,, LTD. has 1 Korean MFDS device approval, 12 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Business overview
Source: DART corporate disclosureFounded in 1998 and listed on KONEX in 2023, ProGen is a biotech venture built on its multi-target fusion protein platform NTIG®. Flagship candidate PG-102 for obesity/diabetes is in Phase 2, oral drug RPG-102 is in Phase 1; its earlier hyFc® platform was applied to EPO, GH, GLP-1 and IL-7. IgE Trap was licensed to GI Innovation for KRW 18.25 billion, and NTIG® was also licensed to Genexine.
Regulatory approvals
data.go.kr1 Korean MFDS device approvals · 2013
- MFDSreagents for clinical enzymesRevoked2013-12-20Product approval · Class 2수허 13-3416 호
Clinical trials
data.go.kr6 MFDS clinical trial authorisations · 2023–2026 (Phase 1 3 · Phase 2 3)
- Phase 1PG-1022026-07-13
1 trial site
- Phase 2PG-1022026-05-18
- Phase 2PG-1022026-02-26
5 trial sites
- Phase 2PG-1022024-07-05
13 trial sites
- Phase 1PG-1022023-08-07
1 trial site
- Phase 1GX-1702023-02-07
3 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matchedPhase 2 · Not yet recruiting · 2026-10 · NCT07677891
Phase 2 · Not yet recruiting · 2026-01 · NCT07187856
Phase 2 · Active not recruiting · 2024-12 · NCT06712615
Phase 1 · Completed · 2024-03 · NCT06309667
R&D and key agreements
Source: DART corporate disclosurePG-102 · 비만 및 당뇨질환 · 임상2상 · Flagship program applying the NTIG® multi-target fusion protein platform
RPG-102 · 비만(경구) · 임상1상 · Oral obesity treatment candidate
근육보존제 및 면역질환 치료제 후보물질 · 근육보존/면역질환 · 디스커버리/비임상 · Early-stage pipeline pursued through domestic and overseas open innovation
Key disclosures
KRX KIND via OpenDARTPublications
PubMed · affiliation-matched- Bispecific GLP-1/GLP-2 agonism in advanced type 2 diabetes: preclinical characterization and a randomized, double-blind, placebo-controlled phase I trial.
Nature communications · 2026-03 · Yang SI, Kim SW, Son KH 외 4
- The brown fat-specific overexpression of RBP4 improves thermoregulation and systemic metabolism by activating the canonical adrenergic signaling pathway.
Experimental & molecular medicine · 2025-03 · Park JY, Ha ES, Lee J 외 6
- SYNCRIP promotes cell cycle progression and lung tumorigenesis by modulating AURKB translation.
Cancer communications (London, England) · 2025-02 · Kim HJ, Ryu HG, Kang M 외 10
- Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy.
Nature communications · 2022-09 · An SB, Yang BG, Jang G 외 26
- Generation and functional characterization of a multigene-modified NK101 cell line exerting diverse mechanisms of antitumor action.
Oncoimmunology · 2022-01 · Hwang I, Jin HT, Kang MC 외 3
- Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer.
Scientific reports · 2020-06 · Youn JI, Park SM, Park S 외 20
- Multivalent DNA vaccine protects against genital herpes by T-cell immune induction in vaginal mucosa.
Antiviral research · 2020-05 · Kim HC, Oh DS, Park JH 외 11
- Expansion of Myeloid-Derived Suppressor Cells Correlates with Renal Progression in Type 2 Diabetic Nephropathy.
Immune network · 2020-04 · Islam J, Lee HJ, Yang SH 외 8
- Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine.
Oncotarget · 2019-09 · Jung DB, Yun M, Kim EO 외 9
- Role of myeloid-derived suppressor cells in immune checkpoint inhibitor therapy in cancer.
Archives of pharmacal research · 2019-07 · Park SM, Youn JI
Show 2 more publications
- Picroside II Isolated from Pseudolysimachion rotundum var. subintegrum Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion.
Molecules (Basel, Switzerland) · 2019-05 · Lee K, Choi J, Choi BK 외 4
- The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine.
Oncotarget · 2015-03 · Jung DB, Yun M, Kim EO 외 9
Patents
KIPRIS · applicant-matchedPCT · Published · 2026-01 · Application PCT/KR2026/000643
Published · 2026-01 · Application 1020260005357
PCT · Published · 2023-12 · Application PCT/KR2023/021957
Published · 2023-12 · Application 1020230195667
Abandoned · 2022-06 · Application 1020220080804
PCT · Published · 2022-01 · Application PCT/KR2022/000243
Registered · 2021-05 · Application 1020210065537
PCT · Published · 2021-05 · Application PCT/KR2021/006069
Rejected · 2021-05 · Application 1020210062471
Withdrawn · 2021-01 · Application 1020210001819
Show 56 more patents
PCT · Published · 2020-12 · Application PCT/KR2020/018595
Withdrawn · 2020-12 · Application 1020200177418
Rejected · 2020-09 · Application 1020200126240
TW · Registered · 2020-07 · Application 109123073
US · Published · 2020-07 · Application 17625460
US · Published · 2020-07 · Application 17625445
EP · Published · 2020-07 · Application 20836293.9
EP · Published · 2020-07 · Application 20837520.4
PCT · Published · 2020-07 · Application PCT/KR2020/008870
PCT · Published · 2020-07 · Application PCT/KR2020/008869
PCT · Published · 2020-07 · Application PCT/KR2020/008871
Withdrawn · 2020-07 · Application 1020200083781
Rejected · 2020-07 · Application 1020200083780
Rejected · 2020-07 · Application 1020200083779
TW · Registered · 2020-05 · Application 109116084
US · Registered · 2020-05 · Application 17611318
EP · Published · 2020-05 · Application 20806219.0
PCT · Published · 2020-05 · Application PCT/KR2020/006346
Registered · 2020-05 · Application 1020217037300
Registered · 2020-05 · Application 1020227019223
Registered · 2019-11 · Application 1020190146310
TW · Published · 2019-01 · Application 108101372
PCT · Published · 2019-01 · Application PCT/KR2019/000524
TW · Published · 2019-01 · Application 108100730
TW · Published · 2019-01 · Application 108100731
PCT · Published · 2019-01 · Application PCT/KR2019/000274
PCT · Published · 2019-01 · Application PCT/KR2019/000270
Registered · 2018-12 · Application 1020180153455
Registered · 2018-11 · Application 1020180136988
CN · Published · 2018-10 · Application 201880083629.3
US · Registered · 2018-10 · Application 16757823
EP · Published · 2018-10 · Application 18871487.7
PCT · Published · 2018-10 · Application PCT/KR2018/012569
JP · Registered · 2018-10 · Application 32542519
Registered · 2018-10 · Application 1020180126625
Rejected · 2018-10 · Application 1020180126659
Registered · 2018-10 · Application 1020180125012
Registered · 2018-09 · Application 1020180106858
Withdrawn · 2017-10 · Application 1020170143080
Withdrawn · 2017-10 · Application 1020170134835
Registered · 2017-02 · Application 1020170025513
US · Registered · 2016-11 · Application 15773855
PCT · Published · 2016-11 · Application PCT/KR2016/012633
PCT · Published · 2016-11 · Application PCT/KR2016/012640
Withdrawn · 2016-11 · Application 1020160147032
PCT · Published · 2016-05 · Application PCT/KR2016/004920
Expired · 2015-11 · Application 1020150154882
Expired · 2015-11 · Application 1020150154893
Withdrawn · 2015-05 · Application 1020150065562
Withdrawn · 2011-12 · Application 1020110134515
Withdrawn · 2011-11 · Application 1020110121150
Rejected · 2007-04 · Application 1020070039548
US · Published · 2004-09 · Application 10595200
PCT · Published · 2004-09 · Application PCT/KR2004/002474
Expired · 2003-10 · Application 1020030068641
Expired · 2001-03 · Application 1020010012987
AI reads
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How to connect (MCP)Companies approved for the same productsBiotech & Drug Discovery
Ranked by how many MFDS product categories overlap. Not a ranking — a pointer to where to look.
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KOSDAQ-listed IVD company using SG Cap™ multiplex diagnostic technology for infectious disease, cancer, and companion animal testing.
Founded in 2002 and KOSDAQ-listed in 2013, Access Bio develops rapid diagnostic tests for malaria, COVID-19, and other infectious diseases.
GC Medical Science Corporation, KOSDAQ-listed since 2014, operates diagnostic reagent, blood glucose, and hemodialysis solution businesses.
Develops SimplexTAS, a point-of-care clinical chemistry and immunoassay analyzer for IVD testing.
KOSDAQ-listed biotech company developing molecular diagnostics with proprietary C-Tag technology and the NeoPlex product line.
Dong-A ST, spun off from Dong-A Socio Holdings in 2013 and KOSPI-listed, makes prescription drugs like Growtropin, Stillen, and Bacchus.
KOSPI-listed in-vitro diagnostics company known for the STANDARD Q antigen/antibody test kits.
KOSDAQ-listed integrated security company behind the V3 antivirus and AhnLab TrusGuard and XDR solutions.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
- Publications
- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
- Patents
- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
- AI visibility
- Measured 2026-10-01
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