Kanaph Therapeutics Inc.
A genome-driven drug developer building bispecific antibody, ADC, and small-molecule pipelines for cancer and eye disease.
As of 2026-10-10, Kanaph Therapeutics Inc. has 4 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Market cap
Business overview
Source: DART corporate disclosureFounded in 2019 and listed on KOSDAQ in 2026, Kanaph Therapeutics Inc. is a drug development company that develops anticancer and ophthalmic disease treatments based on human genome-driven drug discovery technology. Its pipeline includes the bispecific antibody KNP-101 (anti-FAP/IL-12mut), the age-related macular degeneration candidate KNP-301 (C3b/VEGF), small-molecule programs KNP-502, KNP-503, and KNP-504, and the ADC candidate KNP-701 (anti-cMET/anti-EGFR), totaling 7 pipeline and platform programs. The company runs a business model of early out-licensing and co-development with domestic and overseas pharmaceutical companies at the preclinical and early clinical stages, having signed agreements with Dong-A ST, Oscotec, Yuhan, Lotte Biologics, and GC, for cumulative upfront payments of KRW 15.9 billion and total contract value of KRW 774.8 billion.
Products & technology
- KNP-101Next-generation immuno-oncology bispecific antibody targeting FAP and IL-12mut
- KNP-301Bispecific antibody targeting C3b and VEGF for age-related macular degeneration
- KNP-502Small-molecule dual EP2/EP4 inhibitor
- KNP-503Small-molecule SHP2 inhibitor
- KNP-504Small-molecule SOS1 inhibitor
- KNP-701Bispecific ADC targeting anti-cMET and anti-EGFR
R&D and key agreements
Source: DART corporate disclosureADC 플랫폼 기술 (신규 링커 및 페이로드) · ADC platform technology (novel linker and payload) co-developed with Lotte Biologics
Publications
PubMed · affiliation-matched- Harnessing the Potential of FAP-IL12mut TMEkine for Targeted and Enhanced Antitumor Responses.
Molecular cancer therapeutics · 2025-02 · Lee D, Kim D, Kim D 외 9
- Development of a targeted IL-12 immunotherapy platform for B-cell lymphomas.
International immunopharmacology · 2024-09 · Lee D, Kim D, Kim D 외 5
- Pre-Clinical Studies of a Novel Bispecific Fusion Protein Targeting C3b and VEGF in Neovascular and Nonexudative AMD Models.
Ophthalmology and therapy · 2024-08 · Lee Y, Kim D, Chung PED 외 4
- Phase 1b Open-Label Trial of Afatinib Plus Xentuzumab (BI 836845) in Patients With EGFR Mutation-Positive NSCLC After Progression on EGFR Tyrosine Kinase Inhibitors.
JTO clinical and research reports · 2021-09 · Park K, Tan DSW, Su WC 외 10
Patents
KIPRIS · applicant-matchedPCT · Published · 2025-08 · Application PCT/KR2025/012417
Published · 2025-08 · Application 1020250113402
TW · Published · 2024-02 · Application 113105549
TW · Published · 2024-02 · Application 113105550
EP · Published · 2024-02 · Application 24757342.1
EP · Published · 2024-02 · Application 24757341.3
PCT · Published · 2024-02 · Application PCT/KR2024/095358
PCT · Published · 2024-02 · Application PCT/KR2024/095359
Published · 2024-02 · Application 1020240022965
Published · 2024-02 · Application 1020240022981
Show 55 more patents
US · Registered · 2024-01 · Application 18407400
EP · Published · 2024-01 · Application 24738771.5
Published · 2024-01 · Application 1020240002407
PCT · Published · 2024-01 · Application PCT/KR2024/000298
EP · Published · 2023-05 · Application 23807948.7
US · Published · 2023-05 · Application 18867382
PCT · Published · 2023-05 · Application PCT/KR2023/006839
PCT · Published · 2023-02 · Application PCT/KR2023/002611
TW · Registered · 2023-02 · Application 112105417
EP · Published · 2023-02 · Application 23756633.6
US · Published · 2023-02 · Application 18838591
PCT · Published · 2023-02 · Application PCT/KR2023/002224
Registered · 2023-02 · Application 1020230020274
EP · Published · 2023-02 · Application 23753226.2
US · Published · 2023-02 · Application 18836703
PCT · Published · 2023-02 · Application PCT/KR2023/002030
Published · 2023-02 · Application 1020230018031
EP · Published · 2022-12 · Application 22919084.8
US · Published · 2022-12 · Application 18726333
PCT · Published · 2022-12 · Application PCT/KR2022/021371
TW · Published · 2022-08 · Application 111130992
EP · Published · 2022-08 · Application 22858734.1
US · Published · 2022-08 · Application 18684629
PCT · Published · 2022-08 · Application PCT/KR2022/012254
Registered · 2022-08 · Application 1020220102624
TW · Published · 2022-07 · Application 111125765
EP · Published · 2022-07 · Application 22838054.9
PCT · Published · 2022-07 · Application PCT/KR2022/009980
Registered · 2022-07 · Application 1020220084532
Registered · 2022-06 · Application 1020220076968
Published · 2022-05 · Application 1020220062018
Withdrawn · 2022-02 · Application 1020220023930
Published · 2022-01 · Application 1020220001647
EP · Published · 2021-08 · Application 21858650.1
US · Published · 2021-08 · Application 18042352
PCT · Published · 2021-08 · Application PCT/KR2021/011143
Registered · 2021-08 · Application 1020210110489
TW · Registered · 2021-08 · Application 110130721
TW · Registered · 2021-08 · Application 110129665
EP · Published · 2021-08 · Application 21856206.4
EP · Published · 2021-08 · Application 21856207.2
US · Published · 2021-08 · Application 18041392
US · Published · 2021-08 · Application 18040632
PCT · Published · 2021-08 · Application PCT/KR2021/010613
PCT · Published · 2021-08 · Application PCT/KR2021/010611
Registered · 2021-08 · Application 1020210105643
Registered · 2021-08 · Application 1020210105691
TW · Registered · 2021-07 · Application 110125019
EP · Published · 2021-07 · Application 21838564.9
US · Published · 2021-07 · Application 18004613
PCT · Published · 2021-07 · Application PCT/KR2021/008681
PCT · Published · 2021-07 · Application PCT/KR2021/008683
Published · 2021-07 · Application 1020210089021
Published · 2021-07 · Application 1020210089242
Published · 2021-04 · Application 1020210054700
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Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
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- Approvals & clinical trials
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- Key disclosures
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- Measured 2026-10-01
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