ABL Bio Inc.
KOSDAQ-listed antibody biotech developing pipelines via its Grabody™ bispecific antibody platform for global out-licensing.
As of 2026-10-10, ABL Bio Inc. has 28 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Business overview
Source: DART corporate disclosureFounded in 2016 and listed on KOSDAQ in 2018, ABL Bio is an antibody therapeutics R&D company. It develops pipeline candidates based on its proprietary bispecific antibody platform Grabody™ and pursues a business model centered on out-licensing them to global pharmaceutical companies. It applies a strict Decision Review System to decide whether to continue programs, discontinuing early those with limited value upside, shares out-licensing benefits with partners who contributed to development to incentivize co-development, and also pursues in-licensing to expand its pipeline.
Clinical trials
data.go.kr5 MFDS clinical trial authorisations · 2017–2025 (Phase 1 3 · Phase 1/2 1 · Phase 1/2a 1)
- Phase 1/2ABL1032025-06-02
12 trial sites
- Phase 1ABL1032023-08-09
14 trial sites
- Phase 1ABL5032023-03-29
5 trial sites
- Phase 1ABL5012021-08-03
6 trial sites
- Phase 1/2aHDB001A2017-08-29
7 trial sites
Global clinical trials
ClinicalTrials.gov · sponsor-matched- Subsidiary: NEOK Bio, Inc.A Study of NEOK002, an EGFR and MUC1 Targeting Bispecific ADC, in Participants With Select Solid Tumors
Phase 1 · Recruiting · 2026-04 · NCT07612189
- Subsidiary: NEOK Bio, Inc.A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors
Phase 1 · Recruiting · 2026-04 · NCT07612176
Phase 1/2 · Recruiting · 2025-08 · NCT07158918
Phase 1 · Recruiting · 2023-11 · NCT06126666
Phase 1 · Completed · 2022-12 · NCT05756920
Phase 1 · Completed · 2021-10 · NCT05101109
Phase 1 · Recruiting · 2021-04 · NCT04762641
Phase 1 · Completed · 2017-09 · NCT03292783
R&D and key agreements
Source: DART corporate disclosureGrabody™ 이중항체 플랫폼 · 플랫폼 기술 · Proprietary bispecific antibody platform used to develop pipeline candidates for out-licensing
Key disclosures
KRX KIND via OpenDARTShow 12 more events
Publications
PubMed · affiliation-matched- Preclinical development of ABL206, a novel bispecific antibody-drug conjugate targeting B7-H3 and ROR1.
mAbs · 2026-12 · Kwon JA, Lee S, Kim J 외 17
- Expanding the horizons of cancer therapy with next-generation 4-1BB agonists: a review of molecular and clinical strategies to maximize efficacy and ensure safety.
mAbs · 2026-12 · You G, Choi J, Yang C 외 5
- ABL209 (NEOK002): Designing an EGFR × MUC1 Bispecific TOP1i ADC with Promising Antitumor Activity and Enhanced Therapeutic Window.
Molecular cancer therapeutics · 2026-10 · Lee B, Park HJ, Yoo BM 외 14
- A First-in-Human Study of Givastomig, a CLDN18.2 and 4-1BB Bispecific Antibody, as Monotherapy in Patients with CLDN18.2-Positive Advanced or Metastatic Solid Tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2025-12 · Ku G, Shen L, Dayyani F 외 25
- Differential polyamine metabolism in CHO cell lines: Insights into cell growth and antibody quality.
New biotechnology · 2025-09 · Kang DE, Senthilkumar D, Jeon JH 외 4
- A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies.
NPJ Parkinson's disease · 2025-08 · An S, McInnis JJ, Kim D 외 32
- Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor microenvironment.
Journal for immunotherapy of cancer · 2025-02 · Son W, Lee Y, Park Y 외 7
- CLEC12A-directed immunocytokine with target cell-restricted IL-15 activity for treatment of acute myeloid leukemia.
Frontiers in immunology · 2025-01 · Klimovich B, Anton L, Jung J 외 9
- Population pharmacokinetic model of ABL001/CTX-009 (anti-VEGF/DLL4) in adult cancer patients with solid tumor.
Cancer science · 2024-12 · Na JY, Jeon J, Huh KY 외 6
- Anti-4-1BB×PDL1 Bispecific Antibody Reinvigorates Tumor-Specific Exhausted CD8+ T Cells and Enhances the Efficacy of Anti-PD1 Blockade.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2024-09 · Jeon SH, You G, Park J 외 12
Show 18 more publications
- Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production.
ACS synthetic biology · 2024-02 · Kim SH, Park JH, Shin S 외 7
- Asymmetric anti-CLL-1×CD3 bispecific antibody, ABL602 2+1, with attenuated CD3 affinity endows potent antitumor activity but limited cytokine release.
Journal for immunotherapy of cancer · 2023-10 · Lee E, Lee S, Park S 외 6
- CLDN18.2 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN18.2-expressing tumor-directed T-cell activation.
Journal for immunotherapy of cancer · 2023-06 · Gao J, Wang Z, Jiang W 외 17
- Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media.
Applied microbiology and biotechnology · 2023-05 · Kang DE, An YB, Kim Y 외 13
- Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development.
Molecular cancer therapeutics · 2023-01 · You WK, Schuetz TJ, Lee SH
- Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier.
Cell reports methods · 2022-11 · Shin JW, An S, Kim D 외 23
- LAG-3xPD-L1 bispecific antibody potentiates antitumor responses of T cells through dendritic cell activation.
Molecular therapy : the journal of the American Society of Gene Therapy · 2022-08 · Sung E, Ko M, Won JY 외 24
- Conformation-specific Antibodies Targeting Aggregated Forms of α-synuclein Block the Propagation of Synucleinopathy.
Experimental neurobiology · 2022-02 · Choi M, Kim TK, Ahn J 외 8
- Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.
Nature communications · 2021-11 · Byeon IL, Calero G, Wu Y 외 9
- Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockade.
Journal for immunotherapy of cancer · 2021-07 · Jeong S, Park E, Kim HD 외 19
- Bispecific Antibodies: A Smart Arsenal for Cancer Immunotherapies.
Vaccines · 2021-07 · You G, Won J, Lee Y 외 4
- B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes.
Science advances · 2021-01 · You G, Lee Y, Kang YW 외 18
- N-terminal selective conjugation method widens the therapeutic window of antibody-drug conjugates by improving tolerability and stability.
mAbs · 2021-01 · Ko MJ, Song D, Kim J 외 8
- ABL001, a Bispecific Antibody Targeting VEGF and DLL4, with Chemotherapy, Synergistically Inhibits Tumor Progression in Xenograft Models.
International journal of molecular sciences · 2020-12 · Yeom DH, Lee YS, Ryu I 외 9
- Synergistic antitumor activity of a DLL4/VEGF bispecific therapeutic antibody in combination with irinotecan in gastric cancer.
BMB reports · 2020-11 · Kim DH, Lee S, Kang HG 외 10
- Complete 1H, 13C, 15N resonance assignments and secondary structure of the Vpr binding region of hHR23A (residues 223-363).
Biomolecular NMR assignments · 2020-04 · Byeon IL, Jung J, Byeon CH 외 3
- High delta-like ligand 4 expression correlates with a poor clinical outcome in gastric cancer.
Journal of Cancer · 2019-01 · Kim Y, Byeon SJ, Hur J 외 10
- Localization of VEGF to Vascular ECM Is an Important Aspect of Tumor Angiogenesis.
Cancers · 2017-07 · You WK, Stallcup WB
Patents
KIPRIS · applicant-matched- Subsidiary: NEOK Bio, Inc.ANTIBODY-DRUG CONJUGATE OF ANTI-EGFR/MUC1 BISPECIFIC ANTIBODY
PCT · Published · 2026-01 · Application PCT/IB2026/050149
- Subsidiary: NEOK Bio, Inc.ANTIBODY-DRUG CONJUGATE OF ANTI-ROR1/B7-H3 BISPECIFIC ANTIBODY
PCT · Published · 2026-01 · Application PCT/IB2026/050148
PCT · Published · 2025-10 · Application PCT/KR2025/016043
PCT · Published · 2025-09 · Application PCT/US2025/046005
PCT · Published · 2025-03 · Application PCT/KR2025/002878
PCT · Published · 2025-03 · Application PCT/KR2025/099526
US · Published · 2025-01 · Application 19034755
US · Published · 2025-01 · Application 19012836
US · Published · 2024-11 · Application 18935875
CN · Published · 2024-09 · Application 202480061031.X
Show 136 more patents
Published · 2024-09 · Application 1020267012975
EP · Published · 2024-09 · Application 24870938.8
PCT · Published · 2024-09 · Application PCT/CN2024/121653
CN · Published · 2024-09 · Application 202480058733.2
Published · 2024-09 · Application 1020267011345
EP · Published · 2024-09 · Application 24865892.4
PCT · Published · 2024-09 · Application PCT/KR2024/013952
US · Published · 2024-09 · Application 18830263
US · Registered · 2023-10 · Application 18480071
CN · Published · 2023-07 · Application 202380053949.5
Published · 2023-07 · Application 1020257001520
US · Published · 2023-07 · Application 18993148
EP · Published · 2023-07 · Application 23840021.2
PCT · Published · 2023-07 · Application PCT/KR2023/010149
US · Published · 2023-06 · Application 18209299
Published · 2023-05 · Application 1020247041910
EP · Published · 2023-05 · Application 23807084.1
PCT · Published · 2023-05 · Application PCT/CN2023/095544
US · Published · 2022-12 · Application 18063550
Published · 2022-08 · Application 1020220102687
Published · 2022-07 · Application 1020247003739
US · Published · 2022-07 · Application 18580552
EP · Published · 2022-07 · Application 22845538.2
PCT · Published · 2022-07 · Application PCT/IB2022/056679
PCT · Published · 2022-07 · Application PCT/IB2022/056676
TW · Published · 2022-05 · Application 111119008
CN · Published · 2022-05 · Application 202280034495.2
Published · 2022-05 · Application 1020237042723
EP · Published · 2022-05 · Application 22806958.9
US · Registered · 2022-03 · Application 17683869
CN · Published · 2021-08 · Application 202180101592.4
US · Published · 2021-08 · Application 18684660
EP · Published · 2021-08 · Application 21858577.6
PCT · Published · 2021-08 · Application PCT/KR2021/010945
Withdrawn · 2021-05 · Application 1020210065657
Registered · 2020-12 · Application 1020217018612
US · Published · 2020-12 · Application 17789163
EP · Published · 2020-12 · Application 20908197.5
Published · 2020-12 · Application 1020227019355
US · Registered · 2020-12 · Application 17783344
EP · Published · 2020-12 · Application 20898646.3
PCT · Published · 2020-12 · Application PCT/KR2020/018029
Rejected · 2020-11 · Application 1020227021142
US · Published · 2020-11 · Application 17778382
EP · Published · 2020-11 · Application 20889266.1
PCT · Published · 2020-11 · Application PCT/KR2020/016567
PCT · Published · 2020-11 · Application PCT/IB2020/061012
CN · Published · 2020-08 · Application 202110805667.9
CN · Published · 2020-08 · Application 202010852078.1
TW · Published · 2020-08 · Application 109128698
TW · Registered · 2020-08 · Application 112133782
CN · Published · 2020-08 · Application 202080006232.1
Registered · 2020-08 · Application 1020217015572
US · Registered · 2020-08 · Application 17286437
EP · Published · 2020-08 · Application 20851985.0
CN · Published · 2020-07 · Application 202410360186.5
US · Registered · 2020-07 · Application 16940326
US · Registered · 2020-07 · Application 16939536
US · Registered · 2020-07 · Application 16939472
EP · Published · 2020-07 · Application 25169388.3
EP · Published · 2020-07 · Application 20861806.6
EP · Published · 2020-07 · Application 20848658.9
EP · Published · 2020-07 · Application 20848659.7
PCT · Published · 2020-07 · Application PCT/IB2020/000649
PCT · Published · 2020-07 · Application PCT/KR2020/009870
PCT · Published · 2020-07 · Application PCT/KR2020/009871
CN · Published · 2020-06 · Application 202080043719.7
CN · Published · 2020-06 · Application 202310652804.9
Registered · 2020-06 · Application 1020227010688
Registered · 2020-06 · Application 1020217018648
US · Published · 2020-06 · Application 17616799
EP · Published · 2020-06 · Application 23178097.4
EP · Published · 2020-06 · Application 20822425.3
PCT · Published · 2020-06 · Application PCT/KR2020/007704
Withdrawn · 2020-04 · Application 1020200041527
CN · Published · 2020-03 · Application 202080030880.0
Rejected · 2020-03 · Application 1020217028498
US · Published · 2020-03 · Application 17436647
EP · Published · 2020-03 · Application 20765892.3
PCT · Published · 2019-12 · Application PCT/KR2019/018357
CN · Published · 2019-12 · Application 201980078436.3
Registered · 2019-12 · Application 1020217018760
US · Registered · 2019-12 · Application 17296752
EP · Registered · 2019-12 · Application 19890588.7
PCT · Published · 2019-12 · Application PCT/KR2019/016863
Withdrawn · 2019-11 · Application 1020190151539
PCT · Published · 2019-11 · Application PCT/CN2019/120246
Published · 2019-09 · Application 1020190109807
Registered · 2019-08 · Application 1020217008267
US · Registered · 2019-08 · Application 17269784
EP · Published · 2019-08 · Application 19851296.4
PCT · Published · 2019-08 · Application PCT/CN2019/101747
CN · Published · 2019-06 · Application 201980028737.5
Registered · 2019-06 · Application 1020217002319
US · Registered · 2019-06 · Application 17053256
EP · Published · 2019-06 · Application 19826406.1
PCT · Published · 2019-06 · Application PCT/KR2019/007727
CN · Published · 2019-05 · Application 202410586952.X
CN · Published · 2019-05 · Application 201980034890.9
Registered · 2019-05 · Application 1020207037055
US · Registered · 2019-05 · Application 17057643
EP · Published · 2019-05 · Application 19807093.0
PCT · Published · 2019-05 · Application PCT/KR2019/006270
CN · Published · 2019-05 · Application 201980034456.0
Registered · 2019-05 · Application 1020207037054
US · Registered · 2019-05 · Application 17057646
EP · Published · 2019-05 · Application 19806701.9
PCT · Published · 2019-05 · Application PCT/KR2019/006213
CN · Published · 2019-02 · Application 201980079076.9
Registered · 2019-02 · Application 1020217020162
US · Registered · 2019-02 · Application 17298741
EP · Registered · 2019-02 · Application 19890398.1
PCT · Published · 2019-02 · Application PCT/CN2019/075180
CN · Published · 2018-12 · Application 202310369584.9
CN · Published · 2018-12 · Application 201880089354.4
Registered · 2018-12 · Application 1020207009513
US · Registered · 2018-12 · Application 16770728
EP · Published · 2018-12 · Application 24170761.1
EP · Published · 2018-12 · Application 18889608.8
PCT · Published · 2018-12 · Application PCT/KR2018/015953
PCT · Published · 2018-12 · Application PCT/KR2018/015954
CN · Published · 2018-11 · Application 201880074418.3
Registered · 2018-11 · Application 1020180142112
US · Published · 2018-11 · Application 16759937
EP · Published · 2018-11 · Application 18879299.8
PCT · Published · 2018-11 · Application PCT/KR2018/014123
PCT · Published · 2018-05 · Application PCT/KR2018/005968
PCT · Published · 2018-05 · Application PCT/KR2018/005854
CN · Published · 2018-01 · Application 201880015254.7
Registered · 2018-01 · Application 1020180001641
US · Registered · 2018-01 · Application 16475853
EP · Published · 2018-01 · Application 18736765.1
Registered · 2014-07 · Application 1020140085332
CN · Published · 2014-06 · Application 201910506833.8
Expired · 2014-06 · Application 1020140077630
CN · Published · 2013-07 · Application 201610937490.7
AI reads
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How to connect (MCP)Companies approved for the same productsBiotech & Drug Discovery
Ranked by how many MFDS product categories overlap. Not a ranking — a pointer to where to look.
KOSPI-listed comprehensive pharma company behind Amaryl diabetes drug and the USD 86.25M HL5101 anticancer out-license deal.
KOSDAQ-listed integrated security company behind the V3 antivirus and AhnLab TrusGuard and XDR solutions.
Drug delivery system company behind the long-acting injectable platform IVL-DrugFluidic and the LNP delivery platform IVL-GeneFluidic.
Organoid-based biotech founded 2018, KOSDAQ-listed 2025, developing the ATORM-C regenerative therapeutic and ODISEI evaluation solution.
EDGC, a Korea-US joint venture of Eone Medical Foundation and Diagnomics, offers the NIPT service NICE and liquid biopsy OncoCatch.
A diversified SK group company operating eco-friendly chemical materials alongside pharmaceutical products like Joins and vaccines through subsidiary SK Bioscience.
Genomics and drug developer behind the osteoarthritis drug Acelex and the AI-driven healthcare platform Invites Loop.
KOSDAQ-listed antibody biotech developing the next-generation immuno-oncology candidate Multi-AbKine on its fully human antibody library Ymax®-ABL.
A holding company overseeing 54 affiliates including its main biopharmaceutical subsidiary GC, with no direct product manufacturing of its own.
Founded in 2015 and listed on KOSPI in 2021, Prestige BioPharma develops antibody biosimilars and novel antibody drugs including Tuznue.
KOSDAQ-listed biotech company developing molecular diagnostics with proprietary C-Tag technology and the NeoPlex product line.
SillaJen, Inc., founded in 2006 and listed on KOSDAQ in 2016, develops the oncolytic virus immunotherapy Pexa-Vec.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
- Publications
- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
- Patents
- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
- AI visibility
- Measured 2026-10-01
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