KOMIPHARM INTERNATIONAL CO., LTD.
Founded in 1972 and listed on KOSDAQ in 2001, Komipharm develops veterinary vaccines and the human anticancer drug PAX-1, including an African swine fever vaccine.
As of 2026-10-10, KOMIPHARM INTERNATIONAL CO., LTD. has 1 Korean MFDS drug approval, 25 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
Price
Change
Market cap
Products & technology
- PAX-1 (Comenox)Anticancer, cancer-pain, and antiviral treatment
- Pro-vac PED-FcPorcine epidemic diarrhea vaccine
Regulatory approvals
data.go.kr1 Korean MFDS drug approvals · 2017
- MFDS drug코미아스피린정(수출용)2017-04-27Drug · OTC · Notification201702179
Clinical trials
data.go.kr2 MFDS clinical trial authorisations · 2012–2022 (Phase 2 2)
- Phase 2Panaphix(PAX-1)2022-11-01
3 trial sites
- Phase 2KOMINOX2012-12-28
2 trial sites
R&D and key agreements
Source: DART corporate disclosurePAX-1 교모세포종 · 교모세포종(뇌암) · 임상2상 완료(호주·한국), 2b상 확대임상 준비중 · Completed Phase 2 glioblastoma trials in Australia and Korea and is preparing an expanded Phase 2b trial with more participants.
PAX-1 말기암 통증치료 · 말기암 환자 마약성진통제 저감·대체 · 임상2상 완료(대만·엘살바도르), 다국가 2b상 인허가심사중 · Completed Phase 2 trials in Taiwan and El Salvador and is analyzing results; an open-label Phase 2 trial in hospice patients is under way in El Salvador, and a multinational Phase 2b trial with an extended 8-week dosing period is under regulatory review.
PAX-1 뇌전이암 · 뇌전이암 · 미국 FDA 임상1/2상 승인, 개시준비중 · Received FDA approval for a Phase 1/2 trial for brain-metastasis treatment in the US and is preparing to begin it.
ASF 약독화 생백신 · 아프리카돼지열병(ASF) · 필리핀 야외임상시험 진행중(2026년 7월 종료 목표) · Developed both an injectable and an oral (bait) vaccine in collaboration with Korea's Animal and Plant Quarantine Agency, the National Wildlife Disease Control Institute, and Chonbuk National University's Institute of Zoonotic Disease Research; 13 domestic laboratory trials met all safety criteria. Related research was published in Animals (MDPI) in January 2025 and in Transboundary and Emerging Diseases (Wiley) in July 2025.
Key disclosures
KRX KIND via OpenDARTPublications
PubMed · affiliation-matched- Evaluation of Safety, Immunogenicity, and Protective Efficacy of an Orally Administered African Swine Fever Vaccine Candidate ASFV-G-∆I177L/∆LVR.
Vaccines · 2026-07 · Kim Y, Choi SA, Kim W 외 12
- A Repeated and Delayed Homologous Challenge Study Evaluating the Durability of Protection Induced by the Live Attenuated ASF Vaccine Candidate ASFV-G-ΔI177L/ΔLVR.
Vaccines · 2026-06 · Zheng X, Kim Y, Choi SA 외 13
- Evaluation of Pathogenetic and Immunological Parameters of the Genotype I and II Recombinant African Swine Fever Viruses Detected in Pigs in Vietnam.
Viruses · 2026-05 · Truong AD, Nguyen HTT, Chu NT 외 11
- African Swine Fever Vaccine Candidate ASFV-G-ΔI177L/ΔLVR Protects Against Homologous Virulent Challenge and Exhibits Long-Term Maintenance of Antibodies.
Animals : an open access journal from MDPI · 2025-02 · Choi SA, Kim Y, Lee SJ 외 11
- Safety of Live Attenuated ASFV-G-ΔI177L/ΔLVR Vaccination in Sows With Advanced Pregnancies.
Transboundary and emerging diseases · 2025-01 · Lee SJ, Kim Y, Choi SA 외 12
- Detection of PIK3CA hotspot mutations in canine mammary tumors using droplet digital PCR: tissue validation and liquid biopsy feasibility.
Scientific reports · 2024-10 · Seung BJ, Sur JH
- Regional Variations in and Key Predictors of Feline Tumor Malignancy: A Decade-Long Retrospective Study in Korea.
Animals : an open access journal from MDPI · 2024-10 · Seung BJ, Bae MK, Sur JH
- Clinicopathologic description of a cutaneous melanocytic tumor in a 1-year-old cat.
Veterinary clinical pathology · 2024-09 · Bae MK, Cha JW, Lim HY 외 4
- PD-L1 mRNA and protein expression in canine mammary carcinomas: Correlation with histopathological grade and molecular markers.
Veterinary pathology · 2024-05 · Bae MK, Ko YU, Seung BJ 외 2
- Efficacy of a Novel Multiepitope Vaccine Candidate against Foot-and-Mouth Disease Virus Serotype O and A.
Vaccines · 2022-12 · Chathuranga WAG, Hewawaduge C, Nethmini NAN 외 7
Show 15 more publications
- Phase I clinical trial of KML001 monotherapy in patients with advanced solid tumors.
Expert opinion on investigational drugs · 2020-09 · Kim S, Kim S, Park YS 외 9
- Intracellular sensing of viral genomes and viral evasion.
Experimental & molecular medicine · 2019-12 · Lee HC, Chathuranga K, Lee JS
- Preparation of Squalene Oil-Based Emulsion Adjuvants Employing a Self-Emulsifying Drug Delivery System and Assessment of Mycoplasma hyopneumoniae-Specific Antibody Titers in BALB/c Mice.
Pharmaceutics · 2019-12 · Bastola R, Seo JE, Keum T 외 5
- Determination of Mycoplasma hyopneumoniae-Specific IgG, IgG1, and IgG2a Titers in BALB/c Mice Induced by Mineral Oil-Based Oil-in-Water Emulsion Adjuvants Prepared Using a Self-Emulsifying Drug Delivery System.
AAPS PharmSciTech · 2019-01 · Bastola R, Seo JE, Noh G 외 5
- Antitumoral effect of arsenic compound, sodium metaarsenite (KML001), on multiple myeloma cells.
International journal of oncology · 2017-12 · Kim SJ, Kim ES, Kim S 외 5
- Anti-Salmonella Activity Modulation of Mastoparan V1-A Wasp Venom Toxin-Using Protease Inhibitors, and Its Efficient Production via an Escherichia coli Secretion System.
Toxins · 2017-10 · Ha YJ, Kim SW, Lee CW 외 8
- KML001 and doxercalciferol induce synergistic antileukemic effect in acute lymphoid leukemia cells.
Oncology reports · 2017-07 · Liu Y, Shin DY, Oh S 외 3
- Downregulation of androgen receptors by NaAsO2 via inhibition of AKT-NF-κB and HSP90 in castration resistant prostate cancer.
The Prostate · 2017-07 · Kim Y, Park SE, Moon JW 외 10
- Anti-tumoral effect of arsenic compound, sodium metaarsenite (KML001), in non-Hodgkin's lymphoma: an in vitro and in vivo study.
Investigational new drugs · 2016-02 · Yoon JS, Hwang DW, Kim ES 외 10
- Anti-leukemic effect of sodium metaarsenite (KML001) in acute myeloid leukemia with breaking-down the resistance of cytosine arabinoside.
International journal of oncology · 2015-05 · Yoon JS, Kim ES, Park BB 외 4
- Sodium meta-arsenite prevents the development of autoimmune diabetes in NOD mice.
Toxicology and applied pharmacology · 2015-04 · Lee YS, Kim D, Lee EK 외 3
- Sodium meta-arsenite ameliorates hyperglycemia in obese diabetic db/db mice by inhibition of hepatic gluconeogenesis.
Journal of diabetes research · 2014-01 · Lee YS, Lee EK, Oh HH 외 3
- KML001, a telomere-targeting drug, sensitizes glioblastoma cells to temozolomide chemotherapy and radiotherapy through DNA damage and apoptosis.
BioMed research international · 2014-01 · Woo SR, Ham Y, Kang W 외 5
- Sodium meta-arsenite induces reactive oxygen species-dependent apoptosis, necrosis, and autophagy in both androgen-sensitive and androgen-insensitive prostate cancer cells.
Anti-cancer drugs · 2014-01 · Kim Y, Jeong IG, You D 외 6
- Efficacy of a piglet-specific commercial inactivated vaccine against Porcine circovirus type 2 in clinical field trials.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2013-07 · Han K, Seo HW, Oh Y 외 4
Patents
KIPRIS · applicant-matchedRegistered · 2026-02 · Application 1020260023709
Registered · 2024-12 · Application 1020240196920
Registered · 2023-10 · Application 1020230141851
Registered · 2022-04 · Application 1020220051770
Registered · 2021-02 · Application 1020210019517
Rejected · 2021-01 · Application 1020210011445
Registered · 2020-03 · Application 1020200032198
Registered · 2020-02 · Application 1020200015772
Rejected · 2020-02 · Application 1020200015809
PCT · Published · 2019-11 · Application PCT/KR2019/016771
Show 49 more patents
Registered · 2019-11 · Application 1020190149635
Registered · 2019-10 · Application 1020190136134
Rejected · 2019-10 · Application 1020190123898
Registered · 2019-06 · Application 1020190078280
Registered · 2019-05 · Application 1020190054525
Registered · 2018-12 · Application 1020180163766
Registered · 2018-11 · Application 1020180151647
Registered · 2018-02 · Application 1020180021737
Rejected · 2017-11 · Application 1020170159596
Rejected · 2017-11 · Application 1020170149460
Registered · 2017-10 · Application 1020170138257
PCT · Published · 2017-08 · Application PCT/KR2017/009390
PCT · Published · 2017-06 · Application PCT/KR2017/006150
Registered · 2017-03 · Application 1020170035103
Registered · 2017-01 · Application 1020170000018
Registered · 2016-12 · Application 1020160166928
Registered · 2016-08 · Application 1020160111500
Registered · 2012-08 · Application 1020120087725
PCT · Published · 2011-08 · Application PCT/KR2011/006359
Registered · 2011-05 · Application 1020110051567
Registered · 2010-09 · Application 1020100091251
PCT · Published · 2009-03 · Application PCT/US2009/038104
PCT · Published · 2008-07 · Application PCT/KR2008/004424
Registered · 2008-03 · Application 1020080022113
Registered · 2008-01 · Application 1020080009206
Rejected · 2007-12 · Application 1020070131143
Registered · 2007-09 · Application 1020070096699
Registered · 2007-09 · Application 1020070096698
TW · Published · 2006-05 · Application 095116432
PCT · Published · 2006-05 · Application PCT/KR2006/001731
EP · Published · 2005-05 · Application 05076071.9
PCT · Published · 2005-03 · Application PCT/KR2005/000938
TW · Registered · 2005-03 · Application 094107279
Expired · 2004-12 · Application 1020040101807
Expired · 2004-08 · Application 1020040068570
Rejected · 2004-08 · Application 1020040068571
Expired · 2004-03 · Application 1020040016597
Rejected · 2003-06 · Application 1020030041654
Rejected · 2003-06 · Application 1020030037478
EP · Registered · 2002-04 · Application 08168243.7
EP · Registered · 2002-04 · Application 02722968.1
Withdrawn · 2001-08 · Application 1020010052148
Expired · 2001-05 · Application 1020010028680
Expired · 2000-03 · Application 1020000010653
Rejected · 1998-05 · Application 1019980019544
Expired · 1997-06 · Application 1019970024566
Rejected · 1994-07 · Application 1019940015928
Expired · 1993-07 · Application 1019930013378
Expired · 1986-06 · Application 1019860005236
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How to connect (MCP)Companies in the same categoryPharma & CDMO
Founded in 1941 and listed on the KOSPI in 1975, Ildong Holdings is the holding company of the Ildong Pharmaceutical Group, overseeing pharmaceutical, aesthetic medical device, and drug development affiliates.
Founded in 1941 and listed on the KOSPI in 1975, Yuyu Pharma is a pharmaceutical company with a co-promotion agreement with Dong-A ST for Tanamin.
Founded and listed on the KOSPI in 2016, Il Dong Pharmaceutical manufactures products including the Aronamin vitamin line.
Founded 2000, KOSDAQ-listed 2009, Medy-Tox develops and exports botulinum toxin biopharmaceuticals including Meditoxin and Innotox.
KOSPI-listed comprehensive pharmaceutical company specializing in blood products and vaccines, with FDA-approved immunoglobulin ALYGLO.
KOSPI-listed pharmaceutical company behind Coldwon cold medicine and Jangdaewon probiotics, developing a P-CAB drug pipeline.
Founded 2011, listed 2016 — Samsung Biologics is a biopharma CDMO with 785,000L capacity across five Songdo plants.
Founded in 2006 and listed on KOSDAQ in 2020, Genolution is a molecular diagnostics and RNAi company producing nucleic acid extraction reagents and devices.
Ahn-Gook Pharmaceutical sells the cough/expectorant drug Sinecuran and the eye-health supplement Tobicom.
Founded in 2003 and listed on KOSDAQ in 2015, Corestem Chemon develops stem cell therapies and provides nonclinical CRO services, including the ALS treatment Neuronata-R.
Founded 2005, KOSDAQ-listed 2022, BIO-FD&C develops plant-cell platform-based cosmeceutical materials and biopharma pipelines.
KOSPI-listed comprehensive pharma company behind Amaryl diabetes drug and the USD 86.25M HL5101 anticancer out-license deal.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
- Global clinical trials
- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
- Financials
- DART corporate disclosure filings — annual
- Publications
- PubMed (US National Library of Medicine) — affiliation-matched, updated daily
- Patents
- KIPRIS (Korea Institute of Patent Information) — applicant-matched, updated monthly
- AI reads
- Our server logs, IP-verified every 6 hours
- AI visibility
- Measured 2026-10-01
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