Amicogen, Inc.
KOSDAQ-listed industrial biotech producing cephalosporin precursor enzyme CX and antibody-purification Protein A resin.
As of 2026-10-10, Amicogen, Inc. has 1 Korean MFDS device approval, 27 PubMed-indexed papers on record (counted by the MAA Company Index from its own matching of public databases).
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Market cap
Business overview
Source: DART corporate disclosureFounded in 2000 and listed on KOSDAQ in 2013, Amicogen is an industrial biotech company specializing in specialty pharmaceutical enzymes and enzyme-based bio-materials. It develops and commercializes CX enzyme for manufacturing the cephalosporin precursor 7-ACA, SP enzymes for penicillin-class antibiotics, SC enzymes for cephalosporin-class antibiotics, Protein A resin for antibody purification, and culture media products, alongside healthcare materials (N-acetylglucosamine, D-chiro-inositol, pinitol, collagen peptide/tripeptide) and its K-NUTRA brand business. Since 2020, it has partnered with Lysando of Liechtenstein to commercialize an endolysin enzyme.
Products & technology
- CX enzymeEnzyme for manufacturing 7-ACA, a cephalosporin antibiotic precursor
- SP enzymesSynthetic enzymes for penicillin-class antibiotics including amoxicillin
- SC enzymesSynthetic enzymes for cephalosporin-class antibiotics including cefotaxime
- Protein A resinAffinity chromatography resin for antibody biopharmaceutical purification
- Cell culture mediaCulture media for biopharmaceutical production
- Healthcare materials (N-acetylglucosamine, D-chiro-inositol, pinitol, collagen peptide/tripeptide)Health functional ingredient materials
- K-NUTRAConsumer brand business
- Endolysin enzymeNext-generation antibiotic for treating superbugs
Regulatory approvals
data.go.kr1 Korean MFDS device approvals · 2022
- MFDSChemiluminescence assay(CLIA) analyzer2022-05-31Product approval · Class 1체외 수신 22-963 호
R&D and key agreements
Source: DART corporate disclosure엔돌라이신 효소 · 슈퍼박테리아 감염 · 사업화 추진중 · Collaboration with Lysando (Liechtenstein) since 2020
Key disclosures
KRX KIND via OpenDARTShow 14 more events
Publications
PubMed · affiliation-matched- Effects of collagen tripeptide supplementation on oxidative stress and mitochondrial function in aging.
Nutrition research and practice · 2025-12 · Kim CE, Lee JS, Kim YH 외 3
- Chitooligosaccharides as a potential immune modulator for reducing particulate matter 10-induced inflammation in pulmonary damage models.
Toxicological research · 2025-11 · Park CH, Kim YH, Kim JM 외 1
- Chitooligosaccharides suppress airway inflammation, fibrosis, and mucus hypersecretion in a house dust mite-induced allergy model.
Frontiers in allergy · 2025-01 · Kim YH, Park CH, Kim JM 외 1
- Tacrolimus-loaded chitosan-based nanoparticles as an efficient topical therapeutic for the effective treatment of atopic dermatitis symptoms.
International journal of biological macromolecules · 2024-07 · Lee JS, Oh E, Oh H 외 11
- Liquid collagen from freshwater fish skin ameliorates hydration, roughness and elasticity in photo-aged skin: a randomized, controlled, clinical study.
Nutrition research and practice · 2024-06 · Lee JS, Yoon YC, Kim JM 외 3
- Hydrolyzed Collagen Tripeptide Promotes Longitudinal Bone Growth in Childhood Rats via Increases in Insulin-Like Growth Factor-1 and Bone Morphogenetic Proteins.
Journal of medicinal food · 2023-11 · Leem KH, Kim S, Lim J 외 3
- Super-Antioxidant Vitamin A Derivatives with Improved Stability and Efficacy Using Skin-Permeable Chitosan Nanocapsules.
Antioxidants (Basel, Switzerland) · 2023-10 · Oh H, Lee JS, Kim S 외 3
- N-Acetylglucosamine and its dimer ameliorate inflammation in murine colitis by strengthening the gut barrier function.
Food & function · 2023-09 · Choi SI, Shin YC, Lee JS 외 3
- Efficacy of fermented grain using Bacillus coagulans in reducing visceral fat among people with obesity: a randomized controlled trial.
Frontiers in nutrition · 2023-01 · Cho E, Kim JY, Cho B 외 6
- Low molecular weight chitooligosaccharide inhibits infection of SARS-CoV-2 in vitro.
Journal of applied microbiology · 2022-08 · Jang D, Lee D, Shin YC 외 3
Show 17 more publications
- Dietary Collagen Hydrolysates Retard Estrogen Deficiency-Induced Bone Loss through Blocking Osteoclastic Activation and Enhancing Osteoblastic Matrix Mineralization.
Biomedicines · 2022-06 · Kim SI, Park SH, Na W 외 7
- The Improvement Effect of D-Chiro-Inositol and Ecklonia cava K. in the Rat Model of Polycystic Ovarian Syndrome.
Frontiers in pharmacology · 2022-01 · Yang H, Lee SR, Jo SL 외 5
- A Novel Chitosan Nanosponge as a Vehicle for Transepidermal Drug Delivery.
Pharmaceutics · 2021-08 · Lee JS, Oh H, Kim S 외 3
- Evaluation of the Dose-Dependent Effects of Fermented Mixed Grain Enzyme Food on Adiposity and Its Metabolic Disorders in High-Fat Diet-Induced Obese Mice.
Journal of medicinal food · 2021-08 · Han Y, Shin YC, Kim AH 외 2
- Dietary Collagen Hydrolysates Ameliorate Furrowed and Parched Skin Caused by Photoaging in Hairless Mice.
International journal of molecular sciences · 2021-06 · Kang MK, Kim DY, Oh H 외 8
- Effect of Collagen Tripeptide and Adjusting for Climate Change on Skin Hydration in Middle-Aged Women: A Randomized, Double-Blind, Placebo-Controlled Trial.
Frontiers in medicine · 2020-01 · Tak YJ, Shin DK, Kim AH 외 5
- Enhanced alcohol degradation and hepatic protective effects of an Acetobacter Pasteurianus-derived product, CureZyme-ACE, in an acute intoxication rat model.
Laboratory animal research · 2020-01 · Jeon EJ, Cho YS, Kim AH 외 5
- Purification of plant-derived anti-virus mAb through optimized pH conditions for coupling between protein A and epoxy-activated beads.
PeerJ · 2019-01 · Song I, Kang YJ, Choi SL 외 7
- Antiobesity Effects of Short-Chain Chitosan in Diet-Induced Obese Mice.
Journal of medicinal food · 2018-09 · Do AR, Cho SJ, Cho YY 외 8
- Effects of light-emitting diode (LED) with a mixture of wavelengths on the growth and lipid content of microalgae.
Bioprocess and biosystems engineering · 2018-04 · Ra CH, Sirisuk P, Jung JH 외 2
- Distribution of fibroblast growth factors and their roles in skin fibroblast cell migration.
Molecular medicine reports · 2016-10 · Song YH, Zhu YT, Ding J 외 5
- Orally Available Collagen Tripeptide: Enzymatic Stability, Intestinal Permeability, and Absorption of Gly-Pro-Hyp and Pro-Hyp.
Journal of agricultural and food chemistry · 2016-09 · Sontakke SB, Jung JH, Piao Z 외 1
- Determination of process-related impurities in N-acetylglucosamine prepared by chemical and enzymatic methods: structural elucidation and quantification.
Archives of pharmacal research · 2016-07 · Kim YS, Lee SJ, Choi JY 외 9
- Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice.
Nutrients · 2016-05 · Jung UJ, Cho YY, Choi MS
- Expression and purification of FGF21 in Pichia pastoris and its effect on fibroblast-cell migration.
Molecular medicine reports · 2016-04 · Song Y, Ding J, Jin R 외 5
- A novel psychrophilic alkaline phosphatase from the metagenome of tidal flat sediments.
BMC biotechnology · 2015-01 · Lee DH, Choi SL, Rha E 외 4
- Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method.
Biotechnology and bioengineering · 2005-09 · Kang MJ, Lee YM, Yoon SH 외 6
Patents
KIPRIS · applicant-matchedRegistered · 2026-03 · Application 1020260040959
- Subsidiary: 퓨리오젠 주식회사스페이서를 이용한 IDA 및 Ni가 도입된 아가/아가로스 비드 및 이의 제조방법
Published · 2026-01 · Application 1020260012166
- Subsidiary: 퓨리오젠 주식회사아가/아가로스 비드로부터 양이온 교환수지 및 음이온 교환수지를 제조하는 방법
Published · 2026-01 · Application 1020260004688
Published · 2026-01 · Application 1020260000575
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드 및 이의 제조방법
Registered · 2025-10 · Application 1020250160167
Registered · 2025-09 · Application 1020250124247
PCT · Published · 2025-06 · Application PCT/KR2025/008239
- Subsidiary: 퓨리오젠 주식회사다공성 아가로스 비드
Published · 2025-02 · Application 1020250016667
Registered · 2025-01 · Application 1020250006388
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드 및 이의 제조방법
Published · 2024-10 · Application 1020240138873
Show 108 more patents
- Subsidiary: 퓨리오젠 주식회사이온교환 크로마토그래피용 비드 및 그 제조방법
Published · 2024-10 · Application 1020240138874
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드 및 이의 제조방법
Published · 2024-10 · Application 1020240137929
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드 및 이의 제조방법
Published · 2024-10 · Application 1020240137908
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드
Registered · 2024-10 · Application 1020240136605
- Subsidiary: 퓨리오젠 주식회사POROUS AGAR OR AGAROSE BEADS AND METHOD FOR MANUFACTURING SAME
PCT · Published · 2024-10 · Application PCT/KR2024/096239
- Subsidiary: 퓨리오젠 주식회사POROUS AGAR OR AGAROSE BEADS AND METHOD FOR MANUFACTURING SAME
EP · Published · 2024-10 · Application 24877601.5
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드 및 이의 제조방법
Published · 2024-10 · Application 1020240135861
- Subsidiary: 퓨리오젠 주식회사고체 지지체에 항체정제용 리간드를 도입하는 방법 및 항체정제용 리간드가 도입된 고체 지지체
Published · 2024-01 · Application 1020240004458
- Subsidiary: 퓨리오젠 주식회사아가 또는 아가로스 비드 및 이의 가교방법
Registered · 2024-01 · Application 1020240004457
- Subsidiary: 퓨리오젠 주식회사다공성 아가 또는 아가로스 비드 및 이의 제조방법
Registered · 2023-12 · Application 1020230178083
EP · Published · 2023-10 · Application 23204699.5
US · Published · 2023-10 · Application 18488170
CN · Published · 2023-04 · Application 202310473720.9
EP · Published · 2023-04 · Application 23170055.0
US · Published · 2023-04 · Application 18305522
Registered · 2023-04 · Application 1020230046069
CN · Published · 2023-02 · Application 202310091898.7
Published · 2023-01 · Application 1020230011177
CN · Published · 2022-12 · Application 202211567142.7
EP · Published · 2022-12 · Application 22211393.8
US · Registered · 2022-11 · Application 18056385
Registered · 2022-10 · Application 1020220139497
Registered · 2022-05 · Application 1020220054786
Registered · 2021-12 · Application 1020210187761
PCT · Published · 2021-09 · Application PCT/KR2021/012519
Registered · 2021-09 · Application 1020210119259
CN · Published · 2020-11 · Application 202080093452.2
PCT · Published · 2020-11 · Application PCT/KR2020/016010
Rejected · 2020-09 · Application 1020200118244
Registered · 2020-06 · Application 1020200071053
Registered · 2020-04 · Application 1020200049552
CN · Published · 2020-02 · Application 202080078462.9
PCT · Published · 2020-02 · Application PCT/KR2020/001711
PCT · Published · 2019-12 · Application PCT/KR2019/018460
Registered · 2019-11 · Application 1020190147086
Rejected · 2019-11 · Application 1020190143608
Registered · 2019-09 · Application 1020190114945
PCT · Published · 2019-03 · Application PCT/KR2019/003414
US · Registered · 2019-01 · Application 16240074
US · Registered · 2018-06 · Application 16626774
PCT · Published · 2018-06 · Application PCT/KR2018/007170
Registered · 2018-05 · Application 1020180050877
Registered · 2017-12 · Application 1020170183218
Rejected · 2017-12 · Application 1020170175573
PCT · Published · 2017-08 · Application PCT/KR2017/009330
EP · Registered · 2017-07 · Application 17824562.7
PCT · Published · 2017-07 · Application PCT/KR2017/007248
Registered · 2017-06 · Application 1020170082039
Registered · 2017-06 · Application 1020170080405
Registered · 2017-06 · Application 1020170080410
PCT · Published · 2017-02 · Application PCT/KR2017/001217
Registered · 2016-12 · Application 1020160178299
Registered · 2016-08 · Application 1020160109365
Registered · 2016-07 · Application 1020160085721
PCT · Published · 2015-11 · Application PCT/KR2015/012181
PCT · Published · 2015-11 · Application PCT/KR2015/012095
Registered · 2015-09 · Application 1020150124453
Registered · 2015-01 · Application 1020150008250
EP · Registered · 2013-02 · Application 13742961.9
Registered · 2013-01 · Application 1020130006483
US · Published · 2008-10 · Application 12682493
PCT · Published · 2008-10 · Application PCT/KR2008/005868
Registered · 2008-09 · Application 1020080089857
PCT · Published · 2008-05 · Application PCT/KR2008/002535
US · Published · 2008-04 · Application 12594659
PCT · Published · 2008-04 · Application PCT/KR2008/001960
Rejected · 2008-02 · Application 1020080019353
Registered · 2007-10 · Application 1020070101976
Registered · 2007-10 · Application 1020070101968
Registered · 2007-08 · Application 1020070080086
Registered · 2007-05 · Application 1020070043682
Registered · 2007-04 · Application 1020070033680
Registered · 2006-05 · Application 1020060048614
Registered · 2006-04 · Application 1020060034771
Registered · 2006-04 · Application 1020060032550
EP · Published · 2006-03 · Application 06716555.5
- Subsidiary: Labmaster LTDCONDUCTOR/INSULATOR/POROUS FILM-DEVICE AND ITS USE WITH THE ELECTROCHEMILUMINESCENCE-BASED ANALYTICAL METHODS
PCT · Published · 2006-03 · Application PCT/FI2006/000100
- Subsidiary: Labmaster LTDCONDUCTOR/INSULATOR/POROUS FILM-DEVICE AND ASSOCIATED ELECTROCHEMILUMINESCENCE-BASED ANALYTICAL METHOD
EP · Registered · 2006-03 · Application 06725861.6
Expired · 2005-06 · Application 1020050057923
Expired · 2005-03 · Application 1020050026963
Expired · 2004-12 · Application 1020040108887
US · Published · 2004-03 · Application 10550272
EP · Registered · 2004-03 · Application 04723853.0
PCT · Published · 2004-03 · Application PCT/KR2004/000689
- Subsidiary: Labmaster LTDINSULATOR ELECTRODE DEVICES
PCT · Published · 2003-04 · Application PCT/FI2003/000270
- Subsidiary: Labmaster LTDA flow-through electrode device
EP · Registered · 2003-04 · Application 03712194.4
Abandoned · 2003-03 · Application 1020030019018
Rejected · 2003-01 · Application 1020030004847
Rejected · 2002-12 · Application 1020020079402
Expired · 2002-08 · Application 1020020048622
Expired · 2002-07 · Application 1020020038563
Rejected · 2001-12 · Application 1020010080964
Rejected · 2001-11 · Application 1020010072510
PCT · Published · 2001-11 · Application PCT/KR2001/001984
Expired · 2001-10 · Application 1020010061697
- Subsidiary: Labmaster LTDANALYSIS METHODS FOR HEMOCHROMATOSIS MUTATION
EP · Published · 2001-08 · Application 01960809.0
Expired · 2001-07 · Application 1020010044677
Expired · 2001-07 · Application 1020010041549
PCT · Published · 2001-06 · Application PCT/KR2001/001031
Expired · 2001-03 · Application 1020010016111
Abandoned · 2001-03 · Application 1020010015379
Rejected · 2001-03 · Application 1020010015381
Expired · 2001-03 · Application 1020010015380
Expired · 2001-03 · Application 1020010015378
Rejected · 2000-10 · Application 1020000058749
Rejected · 2000-03 · Application 1020000012882
Rejected · 2000-03 · Application 1020000012881
Expired · 1998-06 · Application 1019980024479
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How to connect (MCP)Companies approved for the same productsBiotech & Drug Discovery
Ranked by how many MFDS product categories overlap. Not a ranking — a pointer to where to look.
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KOSDAQ-listed IVD company producing time-resolved fluorescence immunodiagnostic products under the Exdia TRF brand.
KOSDAQ-listed IVD company using SG Cap™ multiplex diagnostic technology for infectious disease, cancer, and companion animal testing.
Founded in 2011 and KOSDAQ-listed in 2019, Sugentech develops multiplex immunoblot, point-of-care, and digital healthcare diagnostics.
KOSDAQ-listed IVD company selling AlzOn and AlzOn+ blood-based oligomeric beta-amyloid tests for Alzheimer's risk assessment.
GC Medical Science Corporation, KOSDAQ-listed since 2014, operates diagnostic reagent, blood glucose, and hemodialysis solution businesses.
KOSDAQ-listed bioprocess and biomedical company supplying the CELBIC single-use cell culture system and the DxBIC automated analysis system.
Dong-A ST, spun off from Dong-A Socio Holdings in 2013 and KOSPI-listed, makes prescription drugs like Growtropin, Stillen, and Bacchus.
KOSPI-listed in-vitro diagnostics company known for the STANDARD Q antigen/antibody test kits.
KOSDAQ-listed integrated security company behind the V3 antivirus and AhnLab TrusGuard and XDR solutions.
Sources and updates
Counts on this page are not company-reported figures. MAA matched records from DART, the Korean MFDS, the US FDA, ClinicalTrials.gov, PubMed and KIPRIS to this company itself, by business registration number or registered name, never by name similarity. They may differ from figures the company publishes.
- Company basics
- Korea Exchange · DART
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- Compiled from disclosure filings
- Approvals & clinical trials
- Korean MFDS (data.go.kr) · US FDA openFDA — updated weekly
- Key disclosures
- KRX KIND via OpenDART exchange filings — updated daily
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- ClinicalTrials.gov (US NIH) — sponsor-matched, updated weekly
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- AI reads
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- Measured 2026-10-01
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