CRONEX.CO.,LTD
Develops multi-transgenic minipigs for xenotransplantation using native Jeju pigs as source animals.
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Business overview
Source: DART corporate disclosureFounded in 2012 and listed on KONEX in 2015, Cronex is a CDMO specializing in xenotransplantation and minipigs. Using native Jeju pigs as source animals and CRISPR/Cas9 and Cpf1 gene editing, it simultaneously knocks out three or more genes -- alpha-Gal, CMAH, and beta4GALNT2 -- and inserts human immune genes MCP and TBM to develop multi-transgenic pigs with 6-7 edited genes for xenotransplant organ production. In March 2021 it completed a test transplanting the kidney, heart, cornea, and skin of a triple-knockout minipig into a primate simultaneously; it operates an SPF-grade breeding facility in Cheongju and is building the Jeju Minipig Research Center (JMRC), with capacity for 700 concurrently bred animals and annual production of over 1,000, and holds or has filed 6 related patents.
Products & technology
- Transgenic minipig for xenotransplantationProduction of organs for human transplantation (kidney, heart, cornea, skin, etc.)
- Jeju minipig (JMRC-bred)Source animal for preclinical CRO drug and medical device testing
- Medical xenogeneic biomaterials (bio-ink, collagen, cartilage, etc.)Materials for 3D printer bio-ink and medical collagen/cartilage
R&D and key agreements
Source: DART corporate disclosure다중형질전환돼지 개발 · 이종장기이식 · 영장류 이식시험 완료 · Developing pigs with 6-7 edited genes through knockout of immune rejection genes (alpha-Gal, CMAH, beta4GALNT2) and knock-in of human MCP and TBM genes
소형종 미니돼지 개발(비임상 모델) · 육종 및 검증 중 · Since 2015, selectively breeding native Jeju pigs (adult weight 60-80kg) over 7 generations to produce source animals half the size of the original breed
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Sources and updates
- Company basics
- Korea Exchange · DART
- Business content
- Compiled from disclosure filings
- AI visibility
- Measured 2026-08-13
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